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Table 1 Demographic and clinical characteristics of patients with MSA-P, PD 2–5 years duration and healthy controls

From: A distinct neuromelanin magnetic resonance imaging pattern in parkinsonian multiple system atrophy

  MSA-P PD 2–5 years Healthy controls p
N 30 10 10
DEMOGRAPHIC AND CLINICAL CHARACTERISTICS
Sex – males (%) 12 (40%) 8 (80%) 6 (60%) 0.077
Age at MRI (years) 66.8 ± 8.4 66.9 ± 6,1 61.4 ± 7.0 0.161
MSA 2nd consensus criteria   NA NA NA
- Possible MSA 22 (73%)
- Probable MSA 8 (27%)
Time from 1st symptom at MRI, mean ± SD/median (years) 4.6 ± 2.7 /4
(2 missing values)
NA NA NA
Time from diagnosis at MRI, mean ± SD /median (years) 2.4 ± 2.7 /1.2
(2 missing values)
NA NA NA
Presenting symptom   NA NA NA
- motor-parkinsonism 23/28 (82%)
- dysautonomia 4/28 (14%)
- other 1/28 (4%)
(2 missing values)
Presence of cerebellar signs 8/27 (30%)
(3 missing values)
NA NA  
Hoehn & Yahr stage at MRI, mean/median 2.5 ± 0.5/2
(5 missing values)
2,0 ± 0,0/2
(2 missing values)
NA < 0.001
LEDD at MRI (mg/day) 674 ± 483
(4 missing values)
562 ± 279
(1 missing values)
NA 0.527
  1. Bold values mean significant statistical differences
  2. Abbreviations: MSA-P: Multiple system atrophy parkinsonian variant, PD Parkinson disease, MRI Magnetic resonance imaging, NA Not applicable, SD Standard Deviation, LEDD Levodopa equivalent daily dose