Table 1 Demographic and clinical characteristics of patients with MSA-P, PD 2–5 years duration and healthy controls
From: A distinct neuromelanin magnetic resonance imaging pattern in parkinsonian multiple system atrophy
MSA-P | PD 2–5 years | Healthy controls | p | |
|---|---|---|---|---|
N | 30 | 10 | 10 | |
DEMOGRAPHIC AND CLINICAL CHARACTERISTICS | ||||
Sex – males (%) | 12 (40%) | 8 (80%) | 6 (60%) | 0.077 |
Age at MRI (years) | 66.8 ± 8.4 | 66.9 ± 6,1 | 61.4 ± 7.0 | 0.161 |
MSA 2nd consensus criteria | NA | NA | NA | |
- Possible MSA | 22 (73%) | |||
- Probable MSA | 8 (27%) | |||
Time from 1st symptom at MRI, mean ± SD/median (years) | 4.6 ± 2.7 /4 (2 missing values) | NA | NA | NA |
Time from diagnosis at MRI, mean ± SD /median (years) | 2.4 ± 2.7 /1.2 (2 missing values) | NA | NA | NA |
Presenting symptom | NA | NA | NA | |
- motor-parkinsonism | 23/28 (82%) | |||
- dysautonomia | 4/28 (14%) | |||
- other | 1/28 (4%) (2 missing values) | |||
Presence of cerebellar signs | 8/27 (30%) (3 missing values) | NA | NA | |
Hoehn & Yahr stage at MRI, mean/median | 2.5 ± 0.5/2 (5 missing values) | 2,0 ± 0,0/2 (2 missing values) | NA | < 0.001 |
LEDD at MRI (mg/day) | 674 ± 483 (4 missing values) | 562 ± 279 (1 missing values) | NA | 0.527 |