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Fig. 5 | BMC Neurology

Fig. 5

From: Autoimmune glial fibrillary acidic protein astrocytopathy manifesting as subacute meningoencephalitis with descending myelitis: a case report

Fig. 5

Tissue-based and cell-based indirect immunofluorescence assays demonstrating GFAPα–immunoglobulin G (IgG) in CSF from our patient. Astrocytic staining of GFAPα- IgG is prominent in the molecular layer (M) of hippocampus (Panel a) and the granular layer (G) of cerebellum (Panel b). The short radial staining pattern of Bergmann glia in the molecular layer (M) of cerebellum (Panel b) is a characteristic feature of GFAPα - IgG immunoreactivity. CSF is reactive with commercial GFAPα -transfected cells (Shaanxi MYBiotech Co. Ltd., China (Panel c). CSF from idiopathic intracranial hypertension patients served as negative controls (Panel d). (Magnification times: 200X)

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