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Table 1 Baseline characteristics of patients of two groups (N = 191)

From: The association between retinal vessel abnormalities and H-type hypertension

Variable

Isolated hypertension (86)

H-type hypertension (105)

P value

Characteristics

 Age, y, mean ± SD

64.62 ± 10.97

66.29 ± 12.35

0.328

 Sex, male, n (%)

63(73.3%)

76(72.4%)

0.892

 Smoking currently, n (%)

41(47.7%)

53(50.5%)

0.700

 Alcohol use, n (%)

17(19.8%)

29(27.6%)

0.207

 Atrial fibrillation, n (%)

8(9.3%)

4(3.8%)

0.120

 Coronary heart disease, n (%)

8(9.3%)

12(11.4%)

0.633

 Diabetes, n (%)

23(26.7%)

39(37.1%)

0.127

 Hypertension duration, median (IQR)

10.00(5.0,13.00)

12.00(6.00,15.00)

0.145

Laboratory examination, Mean ± SD

 Total cholesterol, mmol/L

3.92 ± 1.03

4.01 ± 0.78

0.489

 Triglyceride, mmol/L

2.07 ± 3.73

1.75 ± 0.87

0.400

 LDL, mmol/L

2.09 ± 0.75

2.21 ± 0.64

0.215

 HDL, mmol/L

1.05 ± 0.31

1.05 ± 0.25

1.000

 Serum creatinine, mmol/L

69.90 ± 19.95

70.75 ± 17.41

0.755

 Homocysteine, µmol/L, median (IQR)

8.50(7.33, 9.33)

14.25(12.23,18.37)

0.000

Retinal vessel abnormalities

 Retinopathy, n (%)

19 (22.1%)

44 (41.9%)

0.004

 Hemangioma, n (%)

14(16.3%)

26 (24.8%)

0.152

 Hemorrhages, n (%)a

1(1.2%)

5 (4.8%)

0.316

 Hard exudates, n (%)

9(10.5%)

21(20.0%)

0.072

 Soft exudates, n (%)

6(7.0%)

11(10.5%)

0.398

 Arteriovenous nicking, n (%)

32(37.2%)

53(50.5%)

0.066

 Vascular curvature, median (IQR)

1.00(1.00,1.00)

1.00(1.00,1.50)

0.511

 Arteriosclerosis grades, median (IQR)

1.00(0.00,1.00)

1.00(0.00,2.00)

0.005

 CRVE,µm

195.98 ± 21.19

194.07 ± 19.10

0.515

 CRAE,µm

113.49 ± 11.72

107.47 ± 13.99

0.002

 AVR

0.58 ± 0.06

0.55 ± 0.06

0.001

  1. Abbreviations: SD standard deviation, IQR interquartile range, LDL low-density lipoprotein, HDL high-density lipoprotein, CRVE central retinal vein equivalent, CRAE, central retinal artery equivalent, AVR arteriole-to-venule ratio
  2. aContinuity correction were used