Table 1 Overview of the study assessment

Interview

• Demographic registry

General condition

√

√

√

√

√

• Past disease history

√

√

√

√

√

• Vascular risk factors (e.g., smoking, alcohol consumption)

√

√

√

√

√

• Family history

√

-

-

-

-

Clinical assessment

• Blood pressure, instant blood sugar

Health condition

√

√

√

√

√

• National Institutes of Health Stroke Scale, Modified Rankin Scale

√

√

√

√

√

• Physical and neurological examination

√

√

-

√

√

Primary outcome measure

Corneal function

√

√

-

√

√

• OSDI

Tear secretion

√

√

-

√

√

• Schirmer test

√

√

-

√

√

• Non-invasive tear film breakup time

√

√

-

√

√

• Thickness of lipid layer of lacrimal film

√

√

-

√

√

• PBR

√

√

-

√

√

• Corneal sensation

Corneal sensation

√

√

-

√

√

• BSCVA

Vision

√

√

-

√

√

• ASOCT

Anterior segment

√

√

-

√

√

• Meibomian gland and

lipid layer

√

√

-

√

√