From: Malignant transformation of pleomorphic xanthoastrocytoma and differential diagnosis: case report
GBM (wild type) | E-GBM | PXA | APXA | Present case (1st resection) | Present case (2nd resection) | |
---|---|---|---|---|---|---|
1p/19q | NA | NA | NA | NA | Intact | 1p; intact, 19q; deletion |
BRAF V600E | Positive (MAF, 16%) | Positive (MAF, 49%) | ||||
CDKN2A/B homozygous deletion | NA | 79% [11] | 93% [7] | Intact | Positive | |
TERT promoter mutation | 54% [11] | 71% [11] | 4% [11] | 23% [11] | Negative | Negative |