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Table 2 Subgroup analyses of the relationship between immediate outcomes of the the IVT/IAT procedure, arterial stenosis, and long-term functional outcomes

From: The prediction of acute ischemic stroke patients’ long-term functional outcomes treated with bridging therapy

Immediate outcome

Arterial stenosis

 

Total

NIHSS improved

P-value

mRS improved

P-value

Barthel index improved

P-value

N

%

N

%

N

%

Unfavorable (2a)

 

Total

30

25

83.3

 

16

53.3

 

16

53.3

 

ICA stenosis

No

18

14

77.8

0.622

10

55.6

0.765

10

55.6

0.765

 

Yes (RI ≥0.75)

12

11

91.7

 

6

50.0

 

6

50.0

 

Favourable (2b,3)

 

Total

62

56

90.3

 

48

77.4

 

39

62.9

 

ICA stenosis

No

32

29

90.6

1.000

30

93.8

0.001

27

84.4

< 0.001

 

Yes (RI ≥0.75)

30

27

90.0

 

18

60.0

 

12

40.0

 

Overall

 

Total

92

81

88.0

 

64

69.6

 

55

59.8

 

ICA stenosis

No

50

43

86.0

0.510

40

80.0

0.018

37

74.0

0.002

 

Yes (RI ≥0.75)

42

38

90.5

 

24

57.1

 

18

42.9

 

Unfavorable (2a)

 

Total

30

25

83.3

 

16

53.3

 

16

53.3

 

VA stenosis

No

6

6

100.0

0.553

6

100.0

0.019

5

83.3

0.175

 

Yes (RI ≥0.75)

24

19

79.2

 

10

41.7

 

11

45.8

 

Favourable (2b,3)

 

Total

62

56

90.3

 

48

77.4

 

39

62.9

 

VA stenosis

No

15

15

100.0

0.321

14

93.3

0.155

15

100.0

0.001

 

Yes (RI ≥0.75)

47

41

87.2

 

34

72.3

 

24

51.1

 

Overall

 

Total

92

81

88.0

 

64

69.6

 

55

59.8

 

VA stenosis

No

21

21

100.0

0.063

20

95.2

0.004

20

95.2

< 0.001

 

Yes (RI ≥0.75)

71

60

84.5

 

44

62.0

 

35

49.3

 
  1. P-value by Chi-square test or Fisher’s exact test where appropriate; IAT Intra-arterial thrombectomy, NIHSS National Institute of Health Stroke Scale, mRS modified Rankin Scale, ICA Internal carotid artery, VA Vertebral artery