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Table 3 Effects of vigorous cool room training on walking, fatigue, and fitness

From: Vigorous cool room treadmill training to improve walking ability in people with multiple sclerosis who use ambulatory assistive devices: a feasibility study

Variable

Pre

Post

Follow-up

Test statistic

p

Post-hoc (p-adj)

M (SD)

M (SD)

M (SD)

Walking

T25FW (s)

15.51 (13.41)

11.45 (10.38)

14.00 (14.07)

11.143

0.004*

t1–2 = 0.012*

t1–3 = 0.237

t2–3 = 0.018*

Fast walking speed (cm/s)

92.15 (61.39)

106.44 (65.74)

103.61 (68.34)

10.286

0.006*

t1–2=0.012*

 

t1–3 = 0.043*

 

t2–3 = 0.237

Self-selected walking speed (cm/s)

61.64 (34.01)

62.86 (29.62)

69.05 (33.27)

2.000

0.368

t1–2 = 0.674

t1–3 = 0.063

t2–3 = 0.237

Fatigue

SF-36 fatigue/energy/vitality

39.29 (17.66)

53.57 (22.68)

47.86 (20.18)

4.105

0.128

t1–2 = 0.039*

t1–3 = 0.225

t2–3 = 0.216

Fatigue Severity Scale (mean score)

4.98 (1.36)

4.11 (1.54)

4.56 (1.03)

0.222

0.895

t1–2 = 0.123

t1–3 = 0.345

t2–3 = 0.398

Modified Fatigue Impact Scale (total score)

52.86 (16.48)

40.00 (15.65)

41.57 (15.26)

5.429

0.066

t1–2 = 0.017*

t1–3 = 0.034*

t2–3 = 0.553

Modified Fatigue Impact Scale (Physical)

25.71 (4.31)

19.29 (6.37)

19.29 (5.50)

8.000

0.018*

t1–2 = 0.024*

t1–3 = 0.018*

t2–3 = 0.932

Modified Fatigue Impact Scale (Cognitive)

22.29 (12.91)

16.29 (8.32)

18.57 (9.57)

6.000

0.050

t1–2 = 0.079

t1–3 = 0.089

t2–3 = 0.172

Modified Fatigue Impact Scale (Psychosocial)

4.86 (1.68)

4.43 (2.07)

3.71 (1.70)

0.737

0.692

t1–2 = 0.131

t1–3 = 0.276

t2–3 = 0.673

Aerobic Fitness

V̇O2 max (mL/min/kg)

18.30 (5.37)

19.50 (5.85)

19.77 (7.23)

0.857

0.651

t1–2 = 0.484

t1–3 = 0.398

t2–3 = 0.735

HR max (beats/min)

147.00 (23.68)

149.71 (23.09)

153.14 (30.28)

1.680

0.432

t1–2 = 0.078

t1–3 = 0.237

t2–3 = 0.611

Maximum Workload (watts)

110.43 (42.91)

123.86 (46.39)

123.43 (46.54)

7.714

0.021*

t1–2 = 0.012*

t1–3 = 0.043*

t2–3 = 0.866

Oxygen Uptake Efficiency Slope (V̇Elog10/V̇O2mL/min)

1466.19 (412.62)

1633.73 (474.79)

1588.36 (502.25)

2.000

0.368

t1–2 = 0.123

t1–3 = 0.237

t2–3 = 1.000

Oxygen Uptake Efficiency Slope (V̇Elog10/V̇O2mL/min/kg)

18.76 (4.21)

21.14 (4.71)

21.30 (6.81)

5.429

0.066

t1–2 = 0.049*

t1–3 = 0.091

t2–3 = 0.735

  1. M Mean, SD Standard deviation p: significance; p-adj: adjusted p value; *p < 0.05; T25FW Timed 25-Foot Walk, s Second, cm centimeter, SF-36 36-Item Short Form Health Survey; mL Milli-liter, min Minute, kg Kilogram, V̇E Ventilation, V̇O2 Oxygen consumption;