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Table 3 Effects of vigorous cool room training on walking, fatigue, and fitness

From: Vigorous cool room treadmill training to improve walking ability in people with multiple sclerosis who use ambulatory assistive devices: a feasibility study

Variable Pre Post Follow-up Test statistic p Post-hoc (p-adj)
M (SD) M (SD) M (SD)
Walking
T25FW (s) 15.51 (13.41) 11.45 (10.38) 14.00 (14.07) 11.143 0.004* t1–2 = 0.012*
t1–3 = 0.237
t2–3 = 0.018*
Fast walking speed (cm/s) 92.15 (61.39) 106.44 (65.74) 103.61 (68.34) 10.286 0.006* t1–2=0.012*
  t1–3 = 0.043*
  t2–3 = 0.237
Self-selected walking speed (cm/s) 61.64 (34.01) 62.86 (29.62) 69.05 (33.27) 2.000 0.368 t1–2 = 0.674
t1–3 = 0.063
t2–3 = 0.237
Fatigue
SF-36 fatigue/energy/vitality 39.29 (17.66) 53.57 (22.68) 47.86 (20.18) 4.105 0.128 t1–2 = 0.039*
t1–3 = 0.225
t2–3 = 0.216
Fatigue Severity Scale (mean score) 4.98 (1.36) 4.11 (1.54) 4.56 (1.03) 0.222 0.895 t1–2 = 0.123
t1–3 = 0.345
t2–3 = 0.398
Modified Fatigue Impact Scale (total score) 52.86 (16.48) 40.00 (15.65) 41.57 (15.26) 5.429 0.066 t1–2 = 0.017*
t1–3 = 0.034*
t2–3 = 0.553
Modified Fatigue Impact Scale (Physical) 25.71 (4.31) 19.29 (6.37) 19.29 (5.50) 8.000 0.018* t1–2 = 0.024*
t1–3 = 0.018*
t2–3 = 0.932
Modified Fatigue Impact Scale (Cognitive) 22.29 (12.91) 16.29 (8.32) 18.57 (9.57) 6.000 0.050 t1–2 = 0.079
t1–3 = 0.089
t2–3 = 0.172
Modified Fatigue Impact Scale (Psychosocial) 4.86 (1.68) 4.43 (2.07) 3.71 (1.70) 0.737 0.692 t1–2 = 0.131
t1–3 = 0.276
t2–3 = 0.673
Aerobic Fitness
V̇O2 max (mL/min/kg) 18.30 (5.37) 19.50 (5.85) 19.77 (7.23) 0.857 0.651 t1–2 = 0.484
t1–3 = 0.398
t2–3 = 0.735
HR max (beats/min) 147.00 (23.68) 149.71 (23.09) 153.14 (30.28) 1.680 0.432 t1–2 = 0.078
t1–3 = 0.237
t2–3 = 0.611
Maximum Workload (watts) 110.43 (42.91) 123.86 (46.39) 123.43 (46.54) 7.714 0.021* t1–2 = 0.012*
t1–3 = 0.043*
t2–3 = 0.866
Oxygen Uptake Efficiency Slope (V̇Elog10/V̇O2mL/min) 1466.19 (412.62) 1633.73 (474.79) 1588.36 (502.25) 2.000 0.368 t1–2 = 0.123
t1–3 = 0.237
t2–3 = 1.000
Oxygen Uptake Efficiency Slope (V̇Elog10/V̇O2mL/min/kg) 18.76 (4.21) 21.14 (4.71) 21.30 (6.81) 5.429 0.066 t1–2 = 0.049*
t1–3 = 0.091
t2–3 = 0.735
  1. M Mean, SD Standard deviation p: significance; p-adj: adjusted p value; *p < 0.05; T25FW Timed 25-Foot Walk, s Second, cm centimeter, SF-36 36-Item Short Form Health Survey; mL Milli-liter, min Minute, kg Kilogram, V̇E Ventilation, V̇O2 Oxygen consumption;