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Table 3 Effects of vigorous cool room training on walking, fatigue, and fitness

From: Vigorous cool room treadmill training to improve walking ability in people with multiple sclerosis who use ambulatory assistive devices: a feasibility study

VariablePrePostFollow-upTest statisticpPost-hoc (p-adj)
M (SD)M (SD)M (SD)
Walking
T25FW (s)15.51 (13.41)11.45 (10.38)14.00 (14.07)11.1430.004*t1–2 = 0.012*
t1–3 = 0.237
t2–3 = 0.018*
Fast walking speed (cm/s)92.15 (61.39)106.44 (65.74)103.61 (68.34)10.2860.006*t1–2=0.012*
 t1–3 = 0.043*
 t2–3 = 0.237
Self-selected walking speed (cm/s)61.64 (34.01)62.86 (29.62)69.05 (33.27)2.0000.368t1–2 = 0.674
t1–3 = 0.063
t2–3 = 0.237
Fatigue
SF-36 fatigue/energy/vitality39.29 (17.66)53.57 (22.68)47.86 (20.18)4.1050.128t1–2 = 0.039*
t1–3 = 0.225
t2–3 = 0.216
Fatigue Severity Scale (mean score)4.98 (1.36)4.11 (1.54)4.56 (1.03)0.2220.895t1–2 = 0.123
t1–3 = 0.345
t2–3 = 0.398
Modified Fatigue Impact Scale (total score)52.86 (16.48)40.00 (15.65)41.57 (15.26)5.4290.066t1–2 = 0.017*
t1–3 = 0.034*
t2–3 = 0.553
Modified Fatigue Impact Scale (Physical)25.71 (4.31)19.29 (6.37)19.29 (5.50)8.0000.018*t1–2 = 0.024*
t1–3 = 0.018*
t2–3 = 0.932
Modified Fatigue Impact Scale (Cognitive)22.29 (12.91)16.29 (8.32)18.57 (9.57)6.0000.050t1–2 = 0.079
t1–3 = 0.089
t2–3 = 0.172
Modified Fatigue Impact Scale (Psychosocial)4.86 (1.68)4.43 (2.07)3.71 (1.70)0.7370.692t1–2 = 0.131
t1–3 = 0.276
t2–3 = 0.673
Aerobic Fitness
V̇O2 max (mL/min/kg)18.30 (5.37)19.50 (5.85)19.77 (7.23)0.8570.651t1–2 = 0.484
t1–3 = 0.398
t2–3 = 0.735
HR max (beats/min)147.00 (23.68)149.71 (23.09)153.14 (30.28)1.6800.432t1–2 = 0.078
t1–3 = 0.237
t2–3 = 0.611
Maximum Workload (watts)110.43 (42.91)123.86 (46.39)123.43 (46.54)7.7140.021*t1–2 = 0.012*
t1–3 = 0.043*
t2–3 = 0.866
Oxygen Uptake Efficiency Slope (V̇Elog10/V̇O2mL/min)1466.19 (412.62)1633.73 (474.79)1588.36 (502.25)2.0000.368t1–2 = 0.123
t1–3 = 0.237
t2–3 = 1.000
Oxygen Uptake Efficiency Slope (V̇Elog10/V̇O2mL/min/kg)18.76 (4.21)21.14 (4.71)21.30 (6.81)5.4290.066t1–2 = 0.049*
t1–3 = 0.091
t2–3 = 0.735
  1. M Mean, SD Standard deviation p: significance; p-adj: adjusted p value; *p < 0.05; T25FW Timed 25-Foot Walk, s Second, cm centimeter, SF-36 36-Item Short Form Health Survey; mL Milli-liter, min Minute, kg Kilogram, V̇E Ventilation, V̇O2 Oxygen consumption;