Vigorous cool room treadmill training to improve walking ability in people with multiple sclerosis who use ambulatory assistive devices: a feasibility study

Table 5 Effects of vigorous cool room training on blood biomarkers

Variable	Pre	Post	Follow-up	Test statistic	p	Post-hoc (p-adj)
Variable	M (SD)	M (SD)	M (SD)	Test statistic	p	Post-hoc (p-adj)
Biomarkers
Brain derived neurotrophic factor at rest (ng/mL)	67.62 (20.43)	63.46 (19.97)	64.76 (16.31)	3.000	0.223	t_1–2 = 0.237
						t_1–3 = 0.345
						t_2–3 = 0.499
Interleukin-6 at rest (ng/mL)	0.0005 (0.0010)	0.0007 (0.0006)	0.0019 (0.0035)	2.533	0.282	t_1–2 = 0.686
						t_1–3 = 0.109
						t_2–3 = 0.225

M Mean, SD Standard deviation; p: significance; p-adj: adjusted p value; *p < 0.05; ng Nanogram, mL, Milli-liter;

ISSN: 1471-2377