Postoperative collateral formation after indirect bypass for hemorrhagic moyamoya disease

BMC Neurology

Table 3 Logistic regression analysis of predictors for postoperative collateral formation

Characteristics	PCF		p value		OR (95% CI)
Characteristics	Good (n = 27)	Poor (n = 37)	Uni	Multi ^a	OR (95% CI)
Age, years	33.3 ± 13.0	38.6 ± 8.3	0.066	0.067	0.948 (0.896–1.004)
Male sex	8 (29.6%)	14 (37.8%)	0.496
History of risk factors
Hypertension	7 (25.9%)	7 (18.9%)	0.504
Smoking	1 (3.7%)	3 (8.1%)	0.483
Diabetes	1 (3.7%)	0 (0.0%)	1.000
Alcohol use	0 (0.0%)	3 (8.1%)	0.999
Hyperlipidemia	1 (3.7%)	1 (2.7%)	0.821
Thyroid disease	1 (3.7%)	2 (5.4%)	0.752
Type of hemorrhage
IVH	14 (51.9%)	19 (51.4%)	0.968
ICH&IVH	5 (18.5%)	10 (27.0%)	0.430
ICH	5 (18.5%)	8 (21.6%)	0.824
SAH	3 (11.1%)	0 (0.0%)	0.999
Hemorrhagic site			0.005	0.006	5.222 (1.605–16.987)
Anterior	20 (74.1%)	14 (37.8%)
Posterior	7 (25.9%)	23 (63.2%)
Suzuki stage			0.823
II	4 (14.8%)	3 (8.1%)
III	12 (44.4%)	21 (56.8%)
IV	9 (33.3%)	12 (32.4%)
V	1 (3.7%)	0 (0.0%)
VI	1 (3.7%)	1 (2.7%)
PCA involvement	8 (29.6%)	4 (10.8%)	0.066	0.067	4.181 (0.906–19.306)
Collateral circulation			0.907
Grade I (1–4)	6 (22.2%)	7 (18.9%)
Grade II (5–8)	19 (70.4%)	29 (78.4%)
Grade III (9–12)	2 (7.4%)	1 (2.7%)
Dilation of AChA-PCoA	18 (66.7%)	30 (81.1%)	0.193
ECA collateral
STA collateral	0 (0.0%)	1 (2.7%)	1.000
MMA collateral	17 (63.0%)	19 (51.4%)	0.356
OA collateral	3 (11.1%)	3 (8.1%)	0.685
The stage of pre-stroke period			0.590
Normal	3 (11.1%)	6 (16.2%)
Stage I	0 (0.0%)	1 (2.7%)
Stage II	9 (33.3%)	9 (24.3%)
Stage III	12 (44.4%)	6 (16.2%)
Stage IV	3 (11.1%)	15 (40.5%)
EDAS surgery	23 (85.2%)	30 (81.1%)	0.668	0.998	0.998 (0.210–4.742)

^aAdjusted for surgical modalities
Abbreviations: AChA Anterior choroidal artery, ECA External carotid artery, EDAS Encephaloduroarteriosynangiosis, CI Confidence intervals, MMA Middle meningeal artery, ICH Intracranial hemorrhage,IVH Intraventricular hemorrhage, OA Occipital artery, OR Odds ratios, PCA Posterior cerebral artery, PCF Postoperative collateral formation, PCoA Posterior communicating artery, SAH Subarachnoid hemorrhage, STA Superficial temporal artery

ISSN: 1471-2377