Table 1 Baseline characteristics of participants according to Non-HDL-C quartiles
Characteristics | Quartiles of Non-HDL, mmol/l | P-value | |||
|---|---|---|---|---|---|
Q1: < 2.35 | Q2: 2.35–3.06 | Q3: 3.07–3.83 | Q4: > 3.83 | ||
n = 514 | n = 510 | n = 511 | n = 508 | ||
Age, (Mean ± SD), years | 66 ± 15 | 65 ± 14 | 65 ± 14 | 63 ± 14 | < 0.001a |
Male, n (%) | 327 (63.6%) | 341 (66.9%) | 321 (62.8%) | 301 (59.3%) | 0.093b |
Medical history | |||||
 Hypertension, n (%) | 269 (52.3%) | 265 (52.0%) | 297 (58.1%) | 301 (59.3%) | 0.030 b |
 Diabetes mellitus, n (%) | 129 (25.1%) | 109 (21.4%) | 91 (17.8%) | 138 (27.2%) | 0.002 b |
 Hyperlipidaemia, n (%) | 14 (2.7%) | 19 (3.7%) | 17 (3.3%) | 25 (4.9%) | 0.293 b |
 Atrial fibrillation, n (%) | 97 (18.9%) | 62 (12.2%) | 44 (8.6%) | 32 (6.3%) | < 0.001 b |
Smoking, n (%) | 213 (41.4%) | 220 (43.1%) | 223 (43.6%) | 208 (40.9%) | 0.787 b |
Alcohol consumption, n (%) | 142 (27.6%) | 141 (27.6%) | 142 (27.8% | 135 (26.6%) | 0.971 b |
TOAST classification | |||||
 Large-artery atherosclerosis, n (%) | 151 (29.4%) | 156 (30.6%) | 179 (35.0%) | 185 (36.4%) | < 0.001b |
 Small-artery occlusion, n (%) | 84 (16.3%) | 112 (22.0%) | 132 (25.8%) | 156 (30.7%) |  |
 Cardioembolic, n (%) | 150 (29.2%) | 130 (25.5%) | 97 (19.0%) | 57 (11.2%) |  |
 Undetermined aetiology, n (%) | 108 (21.0%) | 93 (18.2%) | 87 (17.0%) | 98 (19.3%) |  |
 Other aetiology, n (%) | 21 (4.1%) | 19 (3.7%) | 16 (3.1%) | 12 (2.4%) |  |
NIHSS on admission, median (IQR) | 6 (2–13) | 6 (2–11) | 5 (2–11) | 5 (2–10) | 0.002 c |
SBP, (Mean ± SD), mmHg | 141 ± 22 | 144 ± 23 | 147 ± 24 | 151 ± 23 | < 0.001a |
DBP, (Mean ± SD), mmHg | 82 ± 14 | 85 ± 14 | 87 ± 15 | 88 ± 15 | < 0.001 a |
Glucose, (Mean ± SD), mmol/L | 7.61 ± 2.92 | 7.67 ± 3.06 | 7.62 ± 2.96 | 8.98 ± 4.44 | < 0.001a |
Thrombolysis, n (%) | 31 (6.0%) | 22 (4.3%) | 21 (4.1%) | 33 (6.5%) | 0.216 b |
Thrombectomy, n (%) | 33 (6.4%) | 24 (4.3%) | 22 (4.3%) | 23 (4.5%) | 0.386 b |
Lipid profile | |||||
 TG, (Mean ± SD), mmol/L | 1.11 ± 0.72 | 1.36 ± 0.84 | 1.74 ± 1.03 | 2.53 ± 1.88 | < 0.001a |
 TC, (Mean ± SD), mmol/L | 3.14 ± 0.55 | 3.97 ± 0.41 | 4.63 ± 0.41 | 5.81 ± 0.84 | < 0.001a |
 HDL-C, (Mean ± SD), mmol/L | 1.29 ± 0.41 | 1.25 ± 0.36 | 1.23 ± 0.36 | 1.19 ± 0.35 | 0.001 a |
 LDL-C, (Mean ± SD), mmol/L | 1.58 ± 0.40 | 2.33 ± 0.30 | 2.87 ± 0.36 | 3.79 ± 0.77 | < 0.001a |
 Non-HDL, (Mean ± SD), mmol/L | 1.86 ± 0.36 | 2.72 ± 0.20 | 3.40 ± 0.22 | 4.62 ± 0.78 | < 0.001a |