Skip to main content

Table 1 Baseline characteristics of participants according to Non-HDL-C quartiles

From: Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke

Characteristics Quartiles of Non-HDL, mmol/l P-value
Q1: < 2.35 Q2: 2.35–3.06 Q3: 3.07–3.83 Q4: > 3.83
n = 514 n = 510 n = 511 n = 508
Age, (Mean ± SD), years 66 ± 15 65 ± 14 65 ± 14 63 ± 14 < 0.001a
Male, n (%) 327 (63.6%) 341 (66.9%) 321 (62.8%) 301 (59.3%) 0.093b
Medical history
 Hypertension, n (%) 269 (52.3%) 265 (52.0%) 297 (58.1%) 301 (59.3%) 0.030 b
 Diabetes mellitus, n (%) 129 (25.1%) 109 (21.4%) 91 (17.8%) 138 (27.2%) 0.002 b
 Hyperlipidaemia, n (%) 14 (2.7%) 19 (3.7%) 17 (3.3%) 25 (4.9%) 0.293 b
 Atrial fibrillation, n (%) 97 (18.9%) 62 (12.2%) 44 (8.6%) 32 (6.3%) < 0.001 b
Smoking, n (%) 213 (41.4%) 220 (43.1%) 223 (43.6%) 208 (40.9%) 0.787 b
Alcohol consumption, n (%) 142 (27.6%) 141 (27.6%) 142 (27.8% 135 (26.6%) 0.971 b
TOAST classification
 Large-artery atherosclerosis, n (%) 151 (29.4%) 156 (30.6%) 179 (35.0%) 185 (36.4%) < 0.001b
 Small-artery occlusion, n (%) 84 (16.3%) 112 (22.0%) 132 (25.8%) 156 (30.7%)  
 Cardioembolic, n (%) 150 (29.2%) 130 (25.5%) 97 (19.0%) 57 (11.2%)  
 Undetermined aetiology, n (%) 108 (21.0%) 93 (18.2%) 87 (17.0%) 98 (19.3%)  
 Other aetiology, n (%) 21 (4.1%) 19 (3.7%) 16 (3.1%) 12 (2.4%)  
NIHSS on admission, median (IQR) 6 (2–13) 6 (2–11) 5 (2–11) 5 (2–10) 0.002 c
SBP, (Mean ± SD), mmHg 141 ± 22 144 ± 23 147 ± 24 151 ± 23 < 0.001a
DBP, (Mean ± SD), mmHg 82 ± 14 85 ± 14 87 ± 15 88 ± 15 < 0.001 a
Glucose, (Mean ± SD), mmol/L 7.61 ± 2.92 7.67 ± 3.06 7.62 ± 2.96 8.98 ± 4.44 < 0.001a
Thrombolysis, n (%) 31 (6.0%) 22 (4.3%) 21 (4.1%) 33 (6.5%) 0.216 b
Thrombectomy, n (%) 33 (6.4%) 24 (4.3%) 22 (4.3%) 23 (4.5%) 0.386 b
Lipid profile
 TG, (Mean ± SD), mmol/L 1.11 ± 0.72 1.36 ± 0.84 1.74 ± 1.03 2.53 ± 1.88 < 0.001a
 TC, (Mean ± SD), mmol/L 3.14 ± 0.55 3.97 ± 0.41 4.63 ± 0.41 5.81 ± 0.84 < 0.001a
 HDL-C, (Mean ± SD), mmol/L 1.29 ± 0.41 1.25 ± 0.36 1.23 ± 0.36 1.19 ± 0.35 0.001 a
 LDL-C, (Mean ± SD), mmol/L 1.58 ± 0.40 2.33 ± 0.30 2.87 ± 0.36 3.79 ± 0.77 < 0.001a
 Non-HDL, (Mean ± SD), mmol/L 1.86 ± 0.36 2.72 ± 0.20 3.40 ± 0.22 4.62 ± 0.78 < 0.001a
  1. Abbreviations: TOAST The Trial of ORG 10172 in Acute Stroke Treatment, NHISS National Institutes of Health Stroke Scale, SBP Systolic blood pressure, DBP Diastolic blood pressure, TG Triglyceride, TC Total cholesterol, LDL-C Low-density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol, Non-HDL-C Non-high-density lipoprotein cholesterol
  2. a ANOVA test
  3. b Chi-squared test
  4. c Kruskal–Wallis test