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Table 3 Association of quartiles of Non-HDL-C, LDL-C and haemorrhagic transformation

From: Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke

Variables

Crude

Model 1

Model 2

OR

95% CI

P-value

OR

95% CI

P-value

OR

95% CI

P-value

Non-HDL-C

         

 Q1: < 2.35 mmol/L

2.58

1.67–3.98

< 0.001

2.60

1.68–4.03

< 0.001

1.74

1.09–2.78

0.019

 Q2: 2.35–3.06 mmol/L

2.25

1.45–3.50

< 0.001

2.34

1.50–3.66

< 0.001

2.01

1.26–3.20

0.003

 Q3: 3.07–3.83 mmol/L

1.87

1.19–2.93

0.007

1.88

1.19–2.97

< 0.001

1.76

1.10–2.83

0.019

 Q4: > 3.83 mmol/L

1.00

  

1.00

  

1.00

  

Age (years)

   

1.01

1.00–1.02

0.006

1.01

1.00–1.02

0.136

Sex (female/male)

   

0.53

0.40–0.70

< 0.001

0.52

0.35–0.78

0.002

NIHSS

      

1.08

1.06–1.10

< 0.001

Atrial fibrillation

      

1.68

1.13–2.50

0.011

Smoking

      

1.54

0.99–2.38

0.054

Alcohol consumption

      

0.99

0.65–1.50

0.955

SBP (mmHg)

      

0.99

0.98–1.00

0.002

Thrombolysis

      

2.07

1.25–3.43

0.005

Thrombectomy

      

1.81

1.05–3.12

0.032

TOAST classification (cardioembolic/non cardioembolic)

      

2.07

1.45–2.94

< 0.001

LDL-C

         

 Q1: < 1.99 mmol/L

2.20

1.45–3.33

< 0.001

2.26

< 0.001

1.48–3.44

1.57

1.00–2.47

0.049

 Q2: 1.99–2.56 mmol/L

1.70

1.10–2.62

0.017

1.77

0.011

1.14–2.75

1.51

0.95–2.40

0.079

 Q3: 2.57–3.24 mmol/L

1.83

1.19–2.81

0.006

1.85

0.005

1.20–2.85

1.82

1.16–2.87

0.009

 Q4: > 3.24 mmol/L

1.00

  

1.00

  

1.00

  

Age (years)

   

1.02

1.00–1.03

0.004

1.01

1.00–1.02

0.129

Sex (female/male)

   

0.53

0.40–0.70

< 0.001

0.53

0.35–0.80

0.002

NIHSS

      

1.08

1.06–1.10

< 0.001

Atrial fibrillation

      

1.67

1.12–2.49

0.011

Smoking

      

1.53

0.99–2.36

0.056

Alcohol consumption

      

0.98

0.65–1.49

0.936

SBP (mmHg)

      

0.99

0.00–1.00

0.002

Thrombolysis

      

2.03

1.23–3.36

0.006

Thrombectomy

      

1.81

1.05–3.11

0.033

TOAST classification (cardioembolic/non cardioembolic)

      

2.13

1.50–3.02

< 0.001

  1. Abbreviations: OR Odds ratio, CI Confidence interval, Non-HDL-C Non-high-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, NHISS National Institutes of Health Stroke Scale, SBP Systolic blood pressure, TOAST The Trial of ORG 10172 in Acute Stroke Treatment