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Table 3 Association of quartiles of Non-HDL-C, LDL-C and haemorrhagic transformation

From: Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke

Variables Crude Model 1 Model 2
OR 95% CI P-value OR 95% CI P-value OR 95% CI P-value
Non-HDL-C          
 Q1: < 2.35 mmol/L 2.58 1.67–3.98 < 0.001 2.60 1.68–4.03 < 0.001 1.74 1.09–2.78 0.019
 Q2: 2.35–3.06 mmol/L 2.25 1.45–3.50 < 0.001 2.34 1.50–3.66 < 0.001 2.01 1.26–3.20 0.003
 Q3: 3.07–3.83 mmol/L 1.87 1.19–2.93 0.007 1.88 1.19–2.97 < 0.001 1.76 1.10–2.83 0.019
 Q4: > 3.83 mmol/L 1.00    1.00    1.00   
Age (years)     1.01 1.00–1.02 0.006 1.01 1.00–1.02 0.136
Sex (female/male)     0.53 0.40–0.70 < 0.001 0.52 0.35–0.78 0.002
NIHSS        1.08 1.06–1.10 < 0.001
Atrial fibrillation        1.68 1.13–2.50 0.011
Smoking        1.54 0.99–2.38 0.054
Alcohol consumption        0.99 0.65–1.50 0.955
SBP (mmHg)        0.99 0.98–1.00 0.002
Thrombolysis        2.07 1.25–3.43 0.005
Thrombectomy        1.81 1.05–3.12 0.032
TOAST classification (cardioembolic/non cardioembolic)        2.07 1.45–2.94 < 0.001
LDL-C          
 Q1: < 1.99 mmol/L 2.20 1.45–3.33 < 0.001 2.26 < 0.001 1.48–3.44 1.57 1.00–2.47 0.049
 Q2: 1.99–2.56 mmol/L 1.70 1.10–2.62 0.017 1.77 0.011 1.14–2.75 1.51 0.95–2.40 0.079
 Q3: 2.57–3.24 mmol/L 1.83 1.19–2.81 0.006 1.85 0.005 1.20–2.85 1.82 1.16–2.87 0.009
 Q4: > 3.24 mmol/L 1.00    1.00    1.00   
Age (years)     1.02 1.00–1.03 0.004 1.01 1.00–1.02 0.129
Sex (female/male)     0.53 0.40–0.70 < 0.001 0.53 0.35–0.80 0.002
NIHSS        1.08 1.06–1.10 < 0.001
Atrial fibrillation        1.67 1.12–2.49 0.011
Smoking        1.53 0.99–2.36 0.056
Alcohol consumption        0.98 0.65–1.49 0.936
SBP (mmHg)        0.99 0.00–1.00 0.002
Thrombolysis        2.03 1.23–3.36 0.006
Thrombectomy        1.81 1.05–3.11 0.033
TOAST classification (cardioembolic/non cardioembolic)        2.13 1.50–3.02 < 0.001
  1. Abbreviations: OR Odds ratio, CI Confidence interval, Non-HDL-C Non-high-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, NHISS National Institutes of Health Stroke Scale, SBP Systolic blood pressure, TOAST The Trial of ORG 10172 in Acute Stroke Treatment