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Table 5 Stratified logistic regression analysis to identify variables that modify the correlation between Non-HDL-C and haemorrhagic transformation

From: Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke

  OR (95%CI), P-valuea P for interactiona
Age
 < 60 0.64 (0.47–0.87), P < 0.001 0.021
 ≥ 60 0.95 (0.81–1.12), 0.523  
Sex
 Male 0.78 (0.64–0.96) 0.021 0.188
 Female 0.95 (0.78–1.15) 0.586  
Baseline NIHSS score
 < 15 0.90 (0.76–1.06) 0.217 0.363
 ≥ 15 0.78 (0.59–1.02) 0.069  
Atrial Fibrillation
 No 0.82 (0.69–0.96) 0.016 0.151
 Yes 1.05 (0.78–1.40) 0.760  
Smoking
 No 0.89 (0.74–1.06) 0.190 0.655
 Yes 0.83 (0.66–1.04) 0.109  
Alcohol consumption
 No 0.91 (0.78–1.07) 0.261 0.160
 Yes 0.71 (0.53–0.97) 0.032  
SBP
 < 140 0.91 (0.74–1.11) 0.338 0.404
 ≥ 140 0.80 (0.66–0.98) 0.031  
Reperfusion therapy (Thrombolysis/Thrombectomy)
 No 0.86 (0.74–1.01) 0.070 0.944
 Yes 0.88 (0.62–1.24) 0.452  
Stroke subtype
 Non-cardioembolic 0.79 (0.66–0.95) 0.013 0.134
 Cardioembolic 0.99 (0.79–1.25) 0.953  
  1. aAbove model adjusted for age, sex, National Institutes of Health Stroke Scale scores on admission, atrial fibrillation, smoking, alcohol consumption, systolic blood pressure, thrombolysis, thrombectomy and Stroke subtype. In each case, the model is not adjusted for the stratification variable