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Table 1 Included study data extraction

From: Mindfulness for pain, depression, anxiety, and quality of life in people with spinal cord injury: a systematic review

Study

N

Sample Characteristics

Research Design

Theoretical Framework

Intervention Modality/ Length and Comparator

Mindfulness Components

Outcome Measures

Number of Withdrawals/ Dropouts & Reasons

Results (p values, effect sizes, and 95% CIs where available)

Curtis et al. (2015)

11

Age (M & SD): 48.4 (15)

Gender: 90.9% female

Ethnicity: not reported

Time since injury: M = 157.4 months

Etiology of injury: six traumatic injuries, three non-traumatic, two not reported

Status: five inpatients, six community-dwelling

Pretest-posttest of an eight-week modified yoga programme

Not reported

Modified eight-week yoga programme: one 45–60 min class per week.

No comparator.

Brief (5–10 min) mindfulness meditations focusing on breathing and present moment awareness per class

-Yoga Satisfaction Scale

-Toronto Mindfulness Scale

-Brief Pain Inventory Short-Form

-Pain Catastrophising Scale

-Fatigue Severity Scale

-Positive and Negative Affect Scale

-Cognitive and Affective Mindfulness Scale

6, did not complete course.

No significant changes in depression, pain and pain interference, pain catastrophising, or mindfulness (p > .05)

Curtis et al. (2017)

23

Age (M & SD): Yoga group 47.9 (19.51), control group 54.8 (10.11)

Gender: not reported

Ethnicity: Yoga group 30% Caucasian, 40% south Asian, 10% African-Canadian, 10% east Asian, 10% hispanic. Control group 83.3% Caucasian, 8.3% east Asian, 8.3% other.

Time since injury: not reported

Etiology of injury: Yoga group seven traumatic injuries, three non-traumatic. Control group 8 traumatic, four non-traumatic

Status: not reported

Randomised controlled trial

Not reported

Yoga: Two 50- to 60-min classes per week (approx. 12 h total) for six weeks.

Control: wait-list control.

10–15 min mindfulness meditations (breath awareness) per class

-Acceptance and Action Questionnaire

-Hospital Anxiety and Depression Scale

-General Self-Efficacy Scale

-Post-Traumatic Growth Inventory

-Connor-Davidson Resilience Scale

-Self-Compassion Scale

-Five Facet Mindfulness Questionnaire

-Brief Pain Inventory Short Form

-Pain Catastrophising Scale

5, withdrew for logistical or non-study-related and illness reasons (e.g., unable to provide a doctor’s note to confirm eligibility, moved away, vertigo).

10 of 11 participants completed the yoga intervention.

8 of 12 control participants completed study.

Intervention significantly reduced depression severity (p < 0.05) and improved FFMQ-SF – total scores (p = 0.09), FFMQ-SF – observing scores (p = 0.06), and FFMQ-SF – non-reactivity scores (p = 0.04).

No significant improvements seen in anxiety, pain and pain catastrophising (p >. 05).

Flores et al. (2018)

2

Age (M & SD): Participant 1 39 years, participant 2 31 years

Gender: 100% male

Ethnicity: not reported

Time since injury: two weeks

Etiology of injury: Both traumatic

Status: both inpatients

Case study

Not reported

Virtual reality enhanced Dialectical Behavioral Therapy Mindfulness Skills Training

No comparator

Participants listened to mindfulness recordings between 8 and 10 min in length whilst wearing virtual reality goggles showing the illusion of floating down a 3D computer-generated river

-Beck Depression Inventory Fast Screen

-The Spielberger State-Trait Anxiety Inventory

-Graphic Rating Scale (to measure sadness, fear, anger, guilt, shame, disgust, and joy, and acute stress disorder/PTSD)

None.

No statistical analysis run.

Participant 1 underwent intervention four times: on day one, depression scores reduced from 8 to 6 out of 10 on a numerical rating scale after intervention. Anxiety reduced from 8 to 6 out of 10 after intervention.

Participant 2 underwent intervention twice: on day one, ratings of depression fell from 6 to 5 out of 10 after intervention. Feeling anxious dropped from 7 to 6 out of 10 post-intervention.

Hearn & Finlay (2018)

67

Age (M & SD): Mindfulness group 43.8 (8.7), control group 45.2 (12.2)

Gender: Mindfulness group 53% female, control group 55% female

Ethnicity: Mindfulness group 78% white British, control group 74% white British

Time since injury: Mindfulness group 14% 1–2 years, 62% between 2 and 8 years, 24% 8+ years, control group 19% 1–2 years, 49% between 2 and 8 years, 32% 8+ years

Etiology of injury: Mindfulness group 83% traumatic, 17% non-traumatic, control group 66% traumatic, 19% nontraumatic, 16% did not disclose

Status: community dwelling

Randomised controlled trial

Experiential avoidance and behavioural flexibility

Intervention: eight-week online mindfulness training course delivered via two ten-minute mindfulness meditations per day, on six of seven days per week.

Control: weekly psychoeducational content delivered via email once per week for eight weeks.

Body scanning, breath awareness, mindful movement, acceptance and self-compassion meditations, kindness to others meditations

-Hospital Anxiety and Depression Scale

-World Health Organisation Quality of Life BREF

-Five Facet Mindfulness Questionnaire

-Pain Catastrophising Scale

-Pain intensity and unpleasantness (0–10 numerical rating scale)

10 discontinued mindfulness, 5 discontinued psychoeducation.

9 lost to follow-up.

Reasons for drop out not reported.

At course completion: significant improvements in depression severity (p = .002, partial eta squared (η2p) = .184, 95% CI [− 2.43, − 0.58]), anxiety severity (p = .009, η2p = .137, 95% CI [− 2.60, − 0.40]), pain unpleasantness (p = .009, η2p = .137, 95% CI [− 1.67, − 0.25]), and pain catastrophising (p = .02, η2p = .110, 95% CI [− 4.14, − 0.38])

At three-month follow-up: significant improvements in severity of depression (p = .001, η2p = 0.223, 95% CI [− 3.62, − 1.10]), anxiety (p = .023, η2p = 0.112, 95% CI [− 2.39, − 0.23]), and pain catastrophizing (p = .001, η2p = 0.239, 95% CI [− 5.75, − 1.80]).

Norrbrink Budh et al. (2006)

38

Age (M & SD): Intervention group 53.2 (12.6), control group 49.9 (12.3).

Gender: Intervention group 66.7% female, control group 54.4% female

Ethnicity: not reported

Time since injury: Intervention group 9.9 years (SD 12.8), control group 15.8 years (SD 9.3).

Etiology of injury: Intervention group 51.9% traumatic, 48.1% non-traumatic, control group 90.9% traumatic, 9.1% nontraumatic

Status: community dwelling

Parallel design

Not reported

Intervention: two sessions per week for a ten-week cognitive behaviour driven programme.

Control: no intervention.

Mindfulness and body awareness training

-Pain intensity and unpleasantness (CR10 scale and numerical and verbal rating scale)

-Quality of Sleep Questionnaire

-Nottingham Health Profile part 1 (QoL)

-Hospital Anxiety and Depression Scale

-Sense of Coherence Instrument

-Use of the healthcare system

None.

No significant change in pain intensity, pain unpleasantness, and quality of life.

Anxiety and depression decreased from baseline to the 12-month follow-up.

No statistical tests reported.