Table 2 The information about the candidate SNPs in CYP3A4 and CYP11A1
From: CYP3A4 and CYP11A1 variants are risk factors for ischemic stroke: a case control study
Gene | SNP ID | Chr: Position | Alleles (minor/major) | Frequency (MAF) | HaploReg | |
|---|---|---|---|---|---|---|
Case | Control | |||||
CYP3A4 | rs3735451 | 7:99758352 | C/T | 0.26 | 0.30 | Motifs Changed, Selected eQTL hits |
CYP3A4 | rs4646440 | 7:99763247 | A/G | 0.19 | 0.23 | Promoter histone marks, Enhancer histone marks, DNAse, Proteins bound, Motifs changed, Selected eQTL hits |
CYP3A4 | rs35564277 | 7:99764813 | C/T | 0.06 | 0.07 | Motifs Changed |
CYP3A4 | rs4646437 | 7:99767460 | A/G | 0.11 | 0.13 | Promoter histone marks, Enhancer histone marks, Motifs changed, Selected eQTL hits |
CYP11A1 | rs1484215 | 15:74347768 | T/C | 0.18 | 0.18 | Enhancer histone marks, Motifs changed, Selected eQTL hits |
CYP11A1 | rs12912592 | 15:74363369 | T/G | 0.10 | 0.08 | Enhancer histone marks, Motifs changed, Selected eQTL hits |
CYP11A1 | rs28681535 | 15:74367268 | T/G | 0.43 | 0.45 | Promoter histone marks, Enhancer histone marks, DNAse, Motifs changed |