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Table 3 Relationships between CYP3A4 and CYP11A1 polymorphism and ischemic stroke risk

From: CYP3A4 and CYP11A1 variants are risk factors for ischemic stroke: a case control study

Gene SNP IDModelGenotypeCaseControlAdjusted by age and gender
OR (95%CI)p
CYP3A4
rs3735451
AlleleT7056861.000.039
C2493000.81 (0.66–0.98)
GenotypeTT2562281.00 
CT1932300.74 (0.57–0.97)0.029
CC28350.66 (0.38–1.14)0.135
DominantTT2562281.000.018
CT-CC2212650.73 (0.56–0.95)
RecessiveTT-CT4494581.000.308
CC28350.76 (0.45–1.29)
Log-additive0.78 (0.63–0.96)0.019
CYP3A4
rs4646440
AlleleG7687541.000.046
A1862280.80 (0.64–1.00)
GenotypeGG3072821.00 
GA1541900.72 (0.55–0.95)0.021
AA16190.72 (0.36–1.45)0.362
DominantGG3072821.000.017
GA-AA1702090.72 (0.55–0.94)
RecessiveGG-GA4614721.000.560
AA16190.81 (0.41–1.62)
Log-additive0.77 (0.61–0.97)0.024
  1. SNP single nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
  2. p values were calculated by logistic regression analysis with adjustments for age and gender
  3. p < 0.05 means the data is statistically significant
  4. Bold indicates that the values have statistical significance