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Table 7 Comparisons of clinical characteristics among patients with different genotypes of selected SNPs

From: CYP3A4 and CYP11A1 variants are risk factors for ischemic stroke: a case control study

CharacteristicsCYP3A4 rs3735451CYP3A4 rs4646440
TTTCCCpAAAGGGp
TP (g/L)66.16 ± 6.0264.65 ± 5.3466.79 ± 6.090.02166.98 ± 6.9664.60 ± 5.3366.02 ± 5.920.043
Serum uric acid (μmol/L)290.64 ± 97.14279.93 ± 93.17260.83 ± 72.420.247266.33 ± 61.31280.39 ± 94.51287.64 ± 95.950.583
Blood glucose (mmol/L)6.36 ± 2.056.22 ± 2.336.77 ± 3.190.4846.75 ± 2.926.35 ± 2.596.29 ± 2.020.734
TB (μmol/L)13.78 ± 6.9913.23 ± 5.3214.95 ± 9.030.42216.56 ± 11.6213.36 ± 5.2313.62 ± 6.750.237
TG (mmol/L)1.55 ± 0.881.65 ± 1.241.53 ± 1.220.5961.79 ± 1.431.60 ± 1.021.57 ± 1.060.771
Hemoglobin (g/L)137.07 ± 21.57137.51 ± 22.94130.46 ± 31.220.395133.57 ± 15.59137.31 ± 25.98136.82 ± 21.380.842
TC (mmol/L)3.93 ± 0.993.89 ± 1.053.65 ± 1.190.4643.92 ± 1.133.76 ± 1.103.96 ± 0.980.200
HDL-C (mmol/L)1.10 ± 0.241.09 ± 0.261.03 ± 0.370.4941.01 ± 0.311.07 ± 0.271.11 ± 0.250.203
LDL-C (mmol/L)1.82 ± 0.561.82 ± 0.621.66 ± 0.560.4461.80 ± 0.551.76 ± 0.651.84 ± 0.550.375
CharacteristicsCYP11A1 rs12912592CYP11A1 rs28681535
TTGTGGpTTGTGGp
TP (g/L)65.50 ± 0.5665.32 ± 6.0265.64 ± 5.780.91065.72 ± 5.7565.62 ± 5.8265.46 ± 5.830.946
Serum uric acid (μmol/L)245.50 ± 62.93290.63 ± 99.32284.76 ± 92.300.7442810 ± 87.44284.04 ± 93.26290.48 ± 96.950.749
Blood glucose (mmol/L)4.93 ± 0.216.57 ± 2.346.27 ± 2.230.3976.85 ± 2.926.26 ± 2.126.11 ± 1.960.064
TB (μmol/L)9.33 ± 2.8212.02 ± 4.5814.05 ± 6.840.02513.71 ± 6.9114.23 ± 7.3512.75 ± 4.680.117
TG (mmol/L)0.76 ± 0.391.65 ± 1.281.57 ± 0.990.3421.33 ± 0.531.63 ± 1.051.63 ± 1.220.093
Hemoglobin (g/L)130.67 ± 4.04136.46 ± 27.08136.94 ± 21.840.885137.54 + 15.96136.85 ± 24.84136.31 ± 22.920.932
TC (mmol/L)3.64 ± 0.333.97 ± 1.003.89 ± 1.020.7743.96 ± 0.843.95 ± 1.103.81 ± 0.970.433
HDL-C (mmol/L)1.21 ± 0.351.07 ± 0.241.09 ± 0.260.5791.16 ± 0.271.08 ± 0.251.06 ± 0.240.027
LDL-C (mmol/L)1.86 ± 0.201.84 ± 0.561.81 ± 0.590.8711.88 ± 0.521.83 ± 0.621.75 ± 0.560.311
  1. SNP single nucleotide polymorphism, TP total protein, TB total bilirubin, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  2. p < 0.05 indicates statistical significance
  3. Bold indicates that the values have statistical significance