Variables | Good outcome (mRS Score 0–1) at 90 d, n = 317 | Poor outcome (mRS Score 2–6) at 90 d, n = 71 | P Value |
---|---|---|---|
Age, y, mean ± SD | 65.50 ± 11.14 | 71.23 ± 9.98 | < 0.01∗ |
Women, n (%) | 198 (62%) | 39 (55%) | 0.239 |
Admission NIHSS, median (IQR) | 1.25 (1–2.25) | 2.25 (2–3) | < 0.01∗ |
Past medical history, n (%) | |||
Hypertension | 262 (83%) | 62 (87%) | 0.337 |
Coronary artery disease | 38 (12%) | 13 (18%) | 0.154 |
Atrial fibrillation | 38 (12%) | 14 (20%) | 0.084 |
Diabetes mellitus | 114 (36%) | 28 (39%) | 0.583 |
Hyperlipidemia | 127 (40%) | 35 (30%) | 0.449 |
Stroke | 49 (15%) | 12 (17%) | 0.621 |
Hematencephalon | 32 (10%) | 8 (11%) | 0.712 |
Smoking, n (%) | 61 (19%) | 12 (17%) | 0.648 |
Alcohol, n (%) | 48 (15%) | 8 (11%) | 0.401 |
Carotid atherosclerosis, n (%) | 221 (76%) | 38 (78%) | 0.838 |
TOAST classification, n (%) | 0.349 | ||
Large artery atherosclerosis | 69 (55%) | 19 (70%) | |
Small vessel disease | 44 (35%) | 8 (30%) | |
Cardioembolic | 10 (8%) | 0 (0%) | |
Undetermined | 3 (2%) | 0 (0%) | |
Clinical variables, median (IQR) | |||
FBG, mmol/L | 5.42 (4.86–6.75) | 5.63 (4.88–6.65) | 0.493 |
HbAIc, % | 6.00 (5.50–7.30) | 5.90 (5.60–9.00) | 0.203 |
TC, mmol/L | 4.16 (3.59–4.67) | 5.42 (2.94–4.81) | 0.255 |
TG, mmol/L | 1.31 (0.96–1.86) | 1.29 (0.93–1.51) | 0.456 |
LDL-C, mmol/L | 2.38 (1.99–2.87) | 2.25 (1.45–2.96) | 0.070 |
H-CRP, mg/L | 1.70 (0.80–6.93) | 3.10 (0.70–18.30) | 0.220 |
LP-PLA2, ng/mL | 143.00 (97.00–261.50) | 284.00 (208.00–391.00) | < 0.01∗ |
Hcy, umol/L | 12.50 (9.90–15.50) | 11.30 (10.10–14.60) | 0.328 |
D-Dimer, mg/L | 0.34 (0.25–0.53) | 0.27 (0.38–0.69) | 0.414 |
SVD burden score, median (IQR) | 3 (2–3) | 3 (1–3) | 0.894 |
SVD score is 0, n (%) | 4 (1%) | 2 (3%) | |
SVD score is 1, n (%) | 60 (19%) | 16 (23%) | |
SVD score is 2, n (%) | 94 (30%) | 15 (21%) | |
SVD score is 3, n (%) | 132 (42%) | 30 (42%) | |
SVD score is 4, n (%) | 27 (9%) | 8 (11%) | |
WMH, n (%) | 227 (18%) | 62 (87%) | 0.006∗ |
lacunes, n (%) | 226 (71%) | 59 (83%) | 0.042∗ |
PVS, n (%) | 219 (69%) | 45 (63%) | 0.351 |
CMB, n (%) | 46 (15%) | 11 (16%) | 0.833 |
Fazekas score, median (IQR) | 4 (2.5–6) | 5 (4–6) | < 0.01∗ |
Periventricular WMH score | 2 (1–3) | 3 (2–3) | < 0.01∗ |
Deep WMH score | 3 (1–3) | 3 (2–3) | 0.020∗ |
SVD burden score after 3 months, median (IQR) | 3 (2–3) | 3 (2–3) | 0.667 |
SVD score is 0, n (%) | 4 (1%) | 2 (3%) | |
SVD score is 1, n (%) | 57 (18%) | 13 (18%) | |
SVD score is 2, n (%) | 96 (30%) | 18 (25%) | |
SVD score is 3, n (%) | 133 (42%) | 29 (41%) | |
SVD score is 4, n (%) | 27 (9%) | 9 (13%) | |
Fazekas score after 3 months, median (IQR) | 4 (2.5–6) | 5 (4–6) | < 0.01∗ |
Periventricular WMH score | 2 (1–3) | 3 (2–3) | < 0.01∗ |
Deep WMH score | 3 (1–3) | 3 (2–3) | 0.022∗ |