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Table 1 Clinical profiles of previous cases of cerebral infarction associated with adenomyosis

From: Systemic thromboembolism including multiple cerebral infarctions with middle cerebral artery occlusion caused by the progression of adenomyosis with benign gynecological tumor: a case report

Case

Age

Occurrence during menstruation

CA125

(U/mL)

CA19-9

(U/mL)

D-dimer

(µg/mL)

Hb

(g/dL)

Major cerebral artery

Treatment for CI

Treatment for denomyosis

Recurrence of CI

1 [1]

45

-

159

-

1.1

8.4

Normal

Heparin, antiplatelet therapy

GnRH agonist

-

2 [1]

44

-

-

-

-

7

Normal

Heparin, warfarin

GnRH agonist

-

3 [1]

50

+

42.6

-

0.57

6.9

Normal

Aspirin

GnRH agonist

-

4 [1]

42

+

1750

-

6

8.6

Normal

Antiplatelet therapy

GnRH agonist

+

        

Heparin, warfarin

GnRH agonist

-

5 [6]

59

-

334.8

-

7

-

-

Antithrombotic therapy

-

-

6 [7]

48

-

901

1791

1.9

8.5

Occlusion of the left M1 of MCA

Heparin, warfarin

Hysterectomy

-

7 [8]

49

-

379

69.2

3.99

9.9

Normal

Anticoagulant

Hysterectomy

-

8 [2]

44

+

2115

1824

17

10.3

Severe stenosis in the right M2of MCA

Heparin, rivaroxaban

GnRH agonist

+

         

Hysterectomy

-

9 [3]

42

-

395

-

1.4

-

Occlusion of the left M2 of MCA

Warfarin

-

-

10 [3]

50

-

143

-

3.7

-

After occlusion of the left M1 of MCA,

partial reperfusion of MCA

Rivaroxaban

-

-

11 [4]

34

+

937.1

462.5

1.05

13.4

Normal

-

-

-

12 [4]

37

+

735.7

43.2

12.04

10.8

Normal

-

-

-

13 [4]

46

+

546.5

1076.6

2.34

12.1

Stenosis of the right PCA

-

Hysterectomy

-

14 [5]

34

+

937.7

-

27.4

11.2

Severe stenosis in the right M1 of MCA

Heparin, antiplatelet therapy

-

-

15

48

+

3536.2

892.1

79.3

8.2

Occlusion of the right M1 of MCA

Heparin, edoxaban

Endovascular thrombectomy

Hysterectomy

-

  1. Abbreviations: CA cancer antigen; CI cerebral infarction; GnRH gonadotropin-releasing hormone; Hb hemoglobin concentration; MCA middle cerebral artery; PCA posterior cerebral artery