Table 3 Summary of clinical information of 57 patients with LPIN1-related acute recurrent rhabdomyolysis
Ethnic origin | Numberof cases | Sex | Age at onset | Number ofepisodes | CK peak UI/L | Number ofmuscle biopsies | Numberof deaths | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
M | F | NM | <6Y | 6 ~ 16Y | >16Y | NM | ≤3 | >3 | <1*104 | 1*104~10*104 | >10*104 | NM | ||||
19 | 9 | 8 | 2 | 10 | 1 | 0 | 8 | 10 | 9 | 0 | 5 | 14 | 0 | 2 | 3 | |
Jordan [13] | 8 | 5 | 3 | 0 | 7 | 1 | 0 | 0 | 7 | 1 | 0 | 5 | 3 | 0 | 1 | 1 |
Austria [14] | 5 | 2 | 3 | 0 | 4 | 1 | 0 | 0 | 4 | 1 | 0 | 0 | 5 | 0 | 0 | 0 |
3 | 3 | 0 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | |
3 | 1 | 2 | 0 | 1 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 2 | 1 | |
Belgium [4] | 3 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 1 | 0 | 0 | 2 |
North Africa [4] | 2 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Germany [4] | 2 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 |
2 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | |
2 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | |
Arab [6] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Egypt [4] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Ireland [19] | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Palestine [7] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Canada [20] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Portugal [21] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sri Lanka [22] | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Italy [18] | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Total (%) | 57 | 28/57(49.1) | 24/57(42.1) | 5/57(8.8) | 42/57(73.7) | 5/57(8.8) | 2/57(3.5) | 8/57(14.0) | 41/57(71.9) | 15/57(26.3) | 1/57(1.8) | 16/57(28.1) | 39/57(68.4) | 1/57(1.8) | 9/57(15.8) | 8/57(14.0) |