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Table 2 Baseline characteristics of AIS patients according to PLT tertiles

From: Hemostasis functions are associated with hemorrhagic transformation in non-atrial fibrillation patients: a case-control study

Variables

PLT tertiles

Tertile1 (n=193)

Tertile2 (n=187)

Tertile3 (n=190)

P-value

PLT (×109/L)

< 175

175–222

> 222

 

HT, n (%)

123 (63.7%)

80 (42.8%)

82 (43.2%)

< 0.001

Demographic characteristics

 Age (years)

70.2 ± 11.6

68.9 ± 12.7

67.5 ± 12.8

0.970

 Male, n (%)

147 (76.2%)

130 (69.5%)

111 (58.4%)

0.590

 Baseline SBP (mmHg)

150.0 ± 22.2

157.8 ± 21.8

152.3 ± 24.5

< 0.001

 Baseline DBP (mmHg)

81.6 ± 14.0

83.2 ± 14.2

82.2 ± 13.2

0.732

 NIHSS on admission, median (IQR)

5.0 (3.0–11.0)

4.5 (2.0–9.0)

5.0 (2.0–9.0)

0.028

 CTA, n (%)

16 (8.3%)

26 (13.9%)

22 (11.6%)

0.218

Vascular risk factors, n (%)

 Current smoking

64 (33.2%)

64 (34.2%)

82 (43.2%)

0.028

 Current drinking

80 (41.5%)

74 (39.6%)

74 (38.9%)

< 0.001

 Previous Stroke

26 (13.5%)

20 (10.7%)

26 (13.7%)

0.207

 Hypertension

115 (59.6%)

132 (70.6%)

129 (67.9%)

0.112

 Diabetes

45 (23.3%)

56 (29.9%)

48 (25.3%)

0.294

 CAD

23 (11.9%)

14 (7.5%)

10 (5.3%)

0.010

 Dyslipidemia

12 (6.2%)

13 (7.0%)

12 (6.3%)

0.610

 AF

63 (32.6%)

41 (21.9%)

33 (17.4%)

< 0.001

Hematological variables

 Leukocyte counts (×109/L)

7.4 ± 2.8

7.8 ± 3.0

7.8 ± 2.6

< 0.001

 Erythrocyte counts (×109/L)

4.4 ± 0.6

4.5 ± 0.6

4.4 ± 0.5

0.836

 MPV (fl)

11.3 ± 1.5

10.9 ± 1.4

10.6 ± 1.2

0.007

 PT (s)

14.0 ± 1.1

13.6 ± 1.0

13.5 ± 1.0

< 0.001

 INR

1.1 ± 0.1

1.0 ± 0.1

1.0 ± 0.1

< 0.001

 FIB (g/L)

3.7 ± 1.2

3.7 ± 1.1

4.0 ± 2.3

< 0.001

Stroke etiology, n (%)

   

< 0.001

 Atherosclerosis

126 (68.4%)

137 (73.3%)

142 (74.7%)

 

 Cardioembolism

51 (26.4%)

29 (15.5%)

29 (15.3%)

 

 Small vessel occlusion

2 (1.0%)

1 (0.5%)

1 (0.5%)

 

 Other causes

6 (3.1%)

8 (4.2%)

4 (2.1%)

 

Treatment, n (%)

 Anticoagulant therapy

61 (31.6%)

26 (13.9%)

27 (14.2%)

< 0.001

 Antiplatelet therapy

122 (63.2%)

150 (80.2%)

142 (74.7%)

< 0.001

  1. Abbreviations: PLT, platelet counts; HT, hemorrhagic transformation; SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institute of Health Stroke Scale; CTA, computered tomograhy angiography; CAD, coronary artery disease; AF, atrial fibrillation; MPV, mean platelet volume; PT, prothrombin time; INR, International Normalized Ratio; FIB, fibrinogen