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Table 4 Multivariate logistic regression analysis of predictive factors for HT after subcategorized by AF

From: Hemostasis functions are associated with hemorrhagic transformation in non-atrial fibrillation patients: a case-control study

 

Non-AF

     

AF

     
 

Model 1

 

Model 2

 

Model 3

 

Model 1

 

Model 2

 

Model 3

 
 

adjust OR (95%CI)

P-value

adjust OR (95%CI)

P-value

adjust OR (95%CI)

P-value

adjust OR (95%CI)

P-value

adjust OR (95%CI)

P-value

adjust OR (95%CI)

P-value

PLT

 T1

2.236 (1.220–4.095)

0.009

4.908 (1.930–12.481)

0.001

3.509 (1.268–9.711)

0.016

1.894 (0.467–7.685)

0.371

3.084 (0.448–21.206)

0.252

4.822 (0.561–41.468)

0.152

 T2

0.920 (0.508–1.666)

0.784

1.383 (0.626–3.058)

0.423

1.344 (0.575–3.143)

0.496

1.985 (0.440–8.947)

0.372

1.885 (0.289–12.320)

0.508

1.873 (0.262–13.378)

0.532

 T3

Ref

 

Ref

 

Ref

 

Ref

 

Ref

 

Ref

 

MPV

–

–

0.620 (0.479–0.804)

< 0.001

0.605 (0.455–0.805)

0.001

–

–

1.118 (0.635–1.968)

0.700

1.134 (0.648–1.985)

0.659

PT

–

–

3.774 (0.886–16.074)

0.072

3.500 (0.721–16.997)

0.120

–

–

2.865 (0.093–88.653)

0.548

3.861 (0.102–146.521)

0.466

INR

–

–

0.901 (0.778–1.042)

0.159

0.908 (0.774–1.065)

0.237

–

–

0.927 (0.660–1.304)

0.665

0.902 (0.627–1.298)

0.580

FIB

–

–

1.838 (1.324–2.551)

< 0.001

1.928 (1.346–2.760)

< 0.001

–

–

1.023 (0.726–1.441)

0.897

1.061 (0.735–1.533)

0.752

  1. Notes: Model 1: adjusted sex, age, smoking, drinking, CAD, AF, baseline SBP, NIHSS on admission; Model 2: adjusted for covariates from Model 1 and further adjusted for MPV, PT, INR, FIB and leukocyte counts; Model 3: adjusted for covariates from Model 2 and further adjusted for anticoagulant therapy and antiplatelet therapy
  2. Abbreviations: CI, confidence interval; OR, odds ratio; HT, hemorrhagic transformation; AF, atrial fibrillation; PLT, platelet counts; MPV, mean platelet volume; PT, prothrombin time; INR, International Normalized Ratio; FIB, fibrinogen