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Table 2 Relationship between PDQ-39 scores and presence/absence of “OFF” episodes (N = 722)

From: Real-world assessment of the impact of “OFF” episodes on health-related quality of life among patients with Parkinson’s disease in the United States

PDQ-39 dimensions

Coefficient (95% CI)a

P value

Mobility

+ 7.9 (4.4, 11.4)

<  0.001

Activities of daily living

+ 6.7 (3.2, 10.1)

<  0.001

Emotional well-being

+ 4.5 (0.7, 8.3)

0.019

Stigma

+ 3.0 (−0.1, 6.1)

0.057

Social support

+ 2.3 (−0.7, 5.3)

0.134

Cognitions

+ 6.5 (3.5, 9.4)

<  0.001

Communication

+ 9.0 (6.0, 11.9)

<  0.001

Bodily discomfort

+ 1.7 (−3.0, 6.5)

0.470

Summary index

+ 5.2 (2.8, 7.6)

<  0.001

  1. aEffect coefficient for difference between patients with/without “OFF” episodes from linear regression; + indicates a higher score on the PDQ-39 dimension or summary index, indicating poorer health-related quality of life, in patients with “OFF” episodes compared with patients without “OFF” episodes
  2. CI confidence interval; PDQ-39 39-item Parkinson’s Disease Questionnaire
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BMC Neurology

ISSN: 1471-2377

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