From: Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry
Variable | Univariate analysis | Multivariable analysis | ||
---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | |
Age, per decade | 0.98 (0.75–1.27) | 0.86 | ||
Male sex | 1.32 (0.64–2.73) | 0.45 | ||
White race | 1.06 (0.46–2.42) | > 0.9 | ||
Hispanic ethnicity | 1.44 (0.99–2.10) | 0.05 | Dropped from model due to non-significance | |
Medical history | ||||
Hypertension | 0.94 (0.43–2.06) | 0.87 | ||
Diabetes mellitus | 0.94 (0.46–1.93) | 0.87 | ||
Dyslipidemia | 0.70 (0.33–1.45) | 0.34 | ||
Congestive heart failure | 0.35 (0.12–1.02) | 0.05 | 0.15 (0.05–0.44) | < 0.01 |
Active tobacco use | 0.76 (0.21–2.75) | 0.68 | ||
Prior stroke | 1.86 (0.53–6.47) | 0.33 | ||
Chronic renal insufficiency (stage III/IV or dialysis-dependent) | 0.61 (0.15–2.50) | 0.50 | ||
Chronic obstructive pulmonary disease and/or asthma | 0.39 (0.08–1.97) | 0.26 | ||
Cancer | 2.08 (0.44–9.74) | 0.35 | ||
Baseline NIHSS a | 0.003 (−0.006–0.013) | 0.49 | ||
Imaging | ||||
Cortical infarction | 0.40 (0.14–1.16) | 0.09 | Dropped from model due to non-significance | |
Large vessel occlusion | 0.95 (0.37–1.95) | 0.70 | ||
Laboratory data a | ||||
Admission WBC (× 1000/mL) | 0.02 (0.002–0.04) | 0.03 | Dropped from model due to non-significance | |
Admission lymphocyte count (× 1000/mL) | 0.0001 (−0.12–0.12) | > 0.9 | ||
Admission platelet count (× 1000/mL) | 0.0004 (−0.0003–0.001) | 0.22 | ||
D-dimer (per mcg/mL) | 0.009 (0.002–0.017) | 0.02 | 1.73 (0.98–3.04) | 0.06 |
C-reactive protein (per mg/dL) | 0.001 (−0.0008–0.003) | 0.23 |