Table 2 Top 20 significant clusters of the enriched terms according to p value. A cluster is represented by the most significantly enriched term within it. “Count” is the number of DGEs with membership in the given term. “%” is the percentage of DEGs that are found in the given ontology term. “Log10(P)” is the P-value in log base 10
GO | Category | Description | Count | % | -Log10(P) |
|---|---|---|---|---|---|
GO:0002274 | GO BP | myeloid leukocyte activation | 30 | 20.55 | 17.49 |
GO:0098542 | GO BP | defense response to other organism | 19 | 13.01 | 8.73 |
GO:0030659 | GO CC | cytoplasmic vesicle membrane | 19 | 13.01 | 6.65 |
GO:0045088 | GO BP | regulation of innate immune response | 14 | 9.59 | 6.15 |
GO:0097013 | GO CC | phagocytic vesicle lumen | 3 | 2.05 | 6.06 |
GO:0001816 | GO BP | cytokine production | 18 | 12.33 | 5.83 |
GO:0071276 | GO BP | cellular response to cadmium ion | 5 | 3.42 | 5.55 |
GO:0002697 | GO BP | regulation of immune effector process | 13 | 8.9 | 5.31 |
GO:0005766 | GO CC | primary lysosome | 8 | 5.48 | 5.28 |
GO:0019865 | GO MF | immunoglobulin binding | 4 | 2.74 | 4.91 |
GO:0101002 | GO CC | ficolin-1-rich granule | 8 | 5.48 | 4.76 |
GO:0019221 | GO BP | cytokine-mediated signaling pathway | 16 | 10.96 | 4.56 |
GO:0046916 | GO BP | cellular transition metal ion homeostasis | 6 | 4.11 | 4.29 |
hsa05140 | KEGG Pathway | Leishmaniasis | 5 | 3.42 | 4.09 |
hsa05202 | KEGG Pathway | Transcriptional misregulation in cancer icnacercancer | 7 | 4.79 | 3.94 |
GO:0005811 | GO CC | lipid droplet | 5 | 3.42 | 3.87 |
GO:0050727 | GO BP | regulation of inflammatory response | 11 | 7.53 | 3.71 |
GO:0002762 | GO BP | negative regulation of myeloid leukocyte differentiation | 4 | 2.74 | 3.69 |
GO:0046164 | GO BP | alcohol catabolic process | 4 | 2.74 | 3.49 |
GO:2000116 | GO BP | regulation of cysteine-type endopeptidase deendopeptidase endopeptidase activity endopeptidase activityendopeptidase activityendopeptidase activity | 7 | 4.79 | 3.19 |