Long non-coding RNA H19 expression and functional polymorphism rs217727 are linked to increased ischemic stroke risk

Table 1 Clinical characteristics of study subjects

Characteristics	Cases (n = 114)	Controls (n = 114)	p
Male, n (%)	68 (59.64)	68 (59.64)	0.999^a
Female, n (%)	46 (40.35)	46 (40.35)	0.999^a
Age (years)	65.88 ± 14.44	65.88 ± 14.44	0.999^b
BMI (kg/m2)	25.80 ± 5.21	26.21 ± 4.51	0.523
NIHSS at admission
≤ 6	63 (55.26)	–
≥ 7	51 (44.73)
mRS at 3 months at admission
0–2	31 (29.19%)	–
3–6	83 (72.80%)
mRS at 6 months
0–2	72 (63.15%)	–
3–6	42 (36.84%)
Toast of classification cases n (%)
LAA	34(29.82)
SVO	26(22.8)
CE	26(22.8)
UD	28(24.5)
Vascular risk factors
Hypertension, n (%)	65 (57.02)	31 (27.20)	< 0.001^a
Diabetes, n (%)	35 (30.7)	16 (14.04)	0.003^a
Smoking, n (%)	34 (29.82)	8 (7.02)	< 0.001^a
Drinking, n (%)	16 (14.03)	3 (2.63)	0.005^a
Dyslipidemia	39 (34.21)	24(21.05)	0.026^a

Data were shown as mean ± standard deviation (SD) or as n (%).^aChi-square Test; ^bIndependent two-sample T-test. P–value of < 0.05 was regarded as statistically significant
NIHSS National institutes of health stroke scale, LAA large-artery atherosclerosis, SVO small vessel occlusion, CE cardio embolism, UD undetermined etiology, BMI Body Mass Index

ISSN: 1471-2377