Long non-coding RNA H19 expression and functional polymorphism rs217727 are linked to increased ischemic stroke risk

Table 2 Allele and genotype frequencies of H19 rs217727 for IS patients and the control group

Inheritance model	rs217727 Polymorphism	Cases (%)	Controls (%)	OR (95% CI)	P
Codominant^a	Genotype
	CC	73 (64.03)	82 (71.92)	1
	CT	28 (24.56)	27 (23.68)	1.16 (0.62–2.15)	0.62
	TT	13 (11.40)	5 (4.38)	2.92 (0.91–10.92)	0.04
Dominant^b	CC	73 (64.03)	82 (71.92)	1
Dominant^b	CT + TT	41 (35.96)	32 (28.07)	1.43 (0.82–2.51)	0.20
Recessive^c	CC + CT	101 (88.59)	109 (95.61)	1
Recessive^c	TT	13 (11.40)	5 (4.38)	2.80 (0.96–8.15)	0.04
Over-dominant^d	CC + TT	86 (75.43)	87 (76.31)	1
	CT	28 (24.56)	27 (23.68)	1.04 (0.57–1.92)	0.87
	Allele
	T	54 (23.68)	37 (16.22)	1
	C	174 (76.31)	191 (83.77)	0.62 (0.39–0.99)	0.04

OR odd ratio, CI confidence interval
^aCo-dominant; major allele homozygotes vs. heterozygotes
^bDominant; major allele homozygotes vs. heterozygotes + minor allele homozygotes
^cRecessive; major allelehomozygotes + heterozygotes vs. minor allele homozygotes
^dOver dominant; major allele homozygotes + minor allele homozygotes vs. heterozygotes

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