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Table 5 Prediction of diagnostic value, functional outcome and mortality

From: Long non-coding RNA H19 expression and functional polymorphism rs217727 are linked to increased ischemic stroke risk

Parameter

AUC ± SE

95% CI

P

Optimal threshold

Se (%)

Sp (%)

Diagnostic value

 Expression H19 for first 24 h interval

0.874 ± 0.039

0.796–0.951

< 0.0001

1.246

79.49%

79.49%

 Expression H19 for second 24 h interval

0.813 ± 0.049

0.715–0.910

< 0.0001

1.534

77.5%

75.00%

 Expression H19 for 3rd 24 h interval

0.788 ± 0.052

0.685–0.891

< 0.0001

1.614

75.68%

67.57%

Prediction of functional outcome

 Expression H19 in 24 h

0.571 ± 0.065

0.430–0.707

0.278

3.990

58.98%

64.10%

 Expression H19 in 48 h

0.589 ± 0.070

0.451–0.727

0.168

2.950

52.50%

87.50%

 Expression H19 in 72 h

0.549 ± 0.071

0.409–0.690

0.485

3.615

60.53%

54.05%

Prediction of mortality

 Expression H19 for first 24 h interval

0.566 ± 0.068

0.435–0.698

0.310

2.085

64.10%

48.72%

 Expression H19 for second 24 h interval

0.778 ± 0.051

0.678–0.819

< 0.0001

2.170

75.00%

67.50%

 Expression H19 for 3rd 24 h interval

0.706 ± 0.061

0.586–0.826

0.002

2.061

70.27%

60.53%

  1. Abbreviations: AUC Area Under the Curve, CI Confidence Interval, Se sensitivity, Sp specificity P < 0.05 was considered statistically significant