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Table 1 Demographics, clinical and paraclinical data of the study population

From: The aquaporin4-IgG status and how it affects the clinical features and treatment response in NMOSD patients in Egypt

Age in years (Mean ± SD)

34.9 ± 9.2

Age at disease onset in years (Mean ± SD)

28.9 ± 10.5

Duration to diagnosis in months Median (IQR)

10 (0–180)

Disease duration in months Median (IQR)

52 (8–216)

Number of relapses (Mean ± SD)

4.15 ± 2.3

Baseline EDSS (Mean ± SD)

4.7 ± 2.3

Last assessed EDSS (Mean ± SD)

4.3 ± 2.3

Co-morbid autoimmune diseases (n)

 Organ-specific

15

 Non-organ specific

1

Family history of immune-mediated diseases (n)

 Systemic Lupus erythematosus

2

 Rheumatoid arthritis

3

 Multiple sclerosis

1

MRI cervical spine

 Normal

1

 Lesions < 3 segments

7

 Lesions > 3 segments

46

 Not done

16

MRI thoracic spine

 Normal

3

 Lesions < 3 segments

3

 Lesions > 3 segments

13

 Not done

51

MRI brain

 MS-like lesions (periventricular– Juxta cortical)

5

 Non – specific lesions (migraine-like tiny lesions)

6

 NMOSD typical lesions

59

CSF (n = 20)

 Oligoclonal bands

 

 Positive

9

 Negative

11

IgG index

 High

5

Normal

15

  1. EDSS Expanded Disability Status Scale, IQR Interquartile range, SD Standard Deviation, CSF cerebrospinal fluid, IgG immunoglobulins G, MRI magnetic resonance imaging