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Table 1 Detailed report of brain metastasis from nasopharyngeal carcinoma

From: Long‐term recurrence and brain metastasis of nasopharyngeal carcinoma mimicking cystic radiation encephalopathy relapse: a case report

Author/
year
Sex/
age
Major treatment
for NPC
Site in the brain Systemic
metastasis
Pathology of brain metastatic
focus
EBV detection Time interval
between onset/
diagnosis of NPC and identification of brain metastasis
Perifocal edema of metastases Morphology of brain metastases Enhancement
change
Treatment for brain metastases
Liaw et al./1994 [5] Male/69 nd Bilateral
occipital
+ bone Non-keratinizing squamous cell
carcinoma
nd 2 years + Cystic and Non cystic + Chemoradiotherapy.
Ngan et al./2002 [8] Male/33 Chemoradiotherapy Left occipital + lung Undifferentiated carcinoma + 51 months + Cystic nd Surgery
Özyar et al./2004 [9] Male/41 Radiotherapy Right temporal lobe - Undifferentiated
carcinoma
- 45 months + Non
cystic
Homogenously enhancing Whole brain radiotherapy
Kaidar-Person O et al/2012 [10] Male/56 Chemoradiotherapy Occipital + lung Undifferentiated
carcinoma
+ 3 months nd nd nd Radiotherapy
Kuo CL et al./ 2014 [11] female/37 Chemoradiotherapy Dura and
frontotemporal lobe
- Differentiated non-keratinizing carcinoma + 7 months + Non
cystic
Heterogeneously enhancing Chemoradiotherapy and surgery
Su Z et al/2019 [12] Male/43 Chemoradiotherapy Brain and frontal bone - Undifferentiated non-keratinizing carcinoma - 3.5 years Not obvious Non
cystic
+ Chemoradiotherapy
  1. + Positive or detected, - Negative or not detected; nd Not determined, EBV Epstein-Barr virus, NPC Nasopharyngeal carcinoma