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Fig. 3 | BMC Neurology

Fig. 3

From: Rate of neuropathic progression in hereditary transthyretin amyloidosis with polyneuropathy and other peripheral neuropathies: a systematic review and meta-analysis

Fig. 3

Weighted Mean Annual Rate of Change in NIS Total Score in Studies of Patients with CMT, DPN, and ATTRv-PN. Pooled effect estimates were calculated based on the DerSimonian and Laird random-effects model, weighted by inverse variance. The diamond represents a pooled estimate of the annual rate of change across studies within each disease type. Abbreviations: CI, confidence interval; CMT, Charcot-Marie-Tooth disease; DPN, diabetic peripheral neuropathy; ATTRv-PN, hereditary transthyretin amyloidosis with polyneuropathy; NIS, Neuropathy Impairment Score; PI: principal investigator

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