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Fig. 4 | BMC Neurology

Fig. 4

From: Rate of neuropathic progression in hereditary transthyretin amyloidosis with polyneuropathy and other peripheral neuropathies: a systematic review and meta-analysis

Fig. 4

Weighted Mean Annual Rate of Change of NIS-LL Total Score in Studies of Patients with DPN and ATTRv-PN. Pooled effect estimates were calculated based on the DerSimonian and Laird random-effects model, weighted by inverse variance. The diamond represents a pooled estimate of the annual rate of change across studies within disease type. Abbreviations: CI, confidence interval; DPN, diabetic peripheral neuropathy; ATTRv-PN, hereditary transthyretin amyloidosis with polyneuropathy; NIS-LL, Neuropathy Impairment Score – Lower Limbs; PI: principal investigator

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