Table 1 Baseline characteristics of the study population and bivariate comparisons between favorable and unfavorable outcome patients
From: Persistent inflammation worsens short-term outcomes in massive stroke patients
Favorable functional outcome (n = 41) | Unfavorable functional outcome (n = 98) | p Value | |
|---|---|---|---|
Demographic data | |||
Male | 23 (56.1) | 49 (50) | 0.512 |
Age a | 82 (13) | 81 (11) | 0.931 |
Smoker | 9 (22) | 17 (17.3) | 0.526 |
Alcohol drinker | 3 (7) | 12 (12.2) | 0.553 |
Medical history | |||
Arterial hypertension | 34 (82.9) | 72 (73.4) | 0.232 |
Diabetes mellitus | 10 (24.4) | 39 (39.8) | 0.083 |
Atrial fibrillation | 9 (22.0) | 29 (39.8) | 0.357 |
Coronary artery disease | 1 (2.4) | 7 (7) | 0.436 |
Liver disease | 2 (4.9) | 8 (8.2) | 0.723 |
Kidney disease | 1 (2.4) | 7 (7.1) | 0.436 |
Clinical characteristics | |||
Systolic BP, mmHgb | 150 (132–162) | 147 (138–164) | 0.992 |
Blood glucose, mg/dlb | 5.4 (4.6–6.3) | 6.6 (5.3–8.2) | 0.005* |
Laboratory data | |||
Sodium, mmol/Lb | 141 (139–143) | 140 (139–142) | 0.084 |
Potassium, mmol/Lb | 4.0 (3.7–4.2) | 3.8 (3.5–4.1) | 0.144 |
CRP, mg/L | 6 (3–10) | 7 (3–11) | 0.433 |
NLR at admissionb | 3.3 (2.3–4.9) | 5.1 (4.0–8.3) | 0.002* |
NLR at dischargeb | 3.4 (2.0–5.2) | 4.3 (2.7–6.3) | 0.028* |
Platelet, 109/Lb | 202 (155–239) | 193 (157–237) | 0.900 |
LDL, mmol/Lb | 2.5 (2.1–3.3) | 2.7 (1.9–3.4) | 0.837 |
Total bilirubin, μmol/Lb | 12.1 (9.6–15.9) | 15.2 (10.7–18.9) | 0.080 |
Cystatin C, mg/Lb | 1.0 (1.1–1.2) | 1.1 (1.0–1.3) | 0.922 |
Homocysteine, μmol/Lb | 14.8 (11.5–19.3) | 13.9 (11.1–19.9) | 0.990 |
Imaging data | |||
Cerebral ischemia | 36 (87.8) | 81 (82.7) | 0.448 |
Hemisphere | 6 (16.6) | 40 (49.3) | 0.001* |
Lobes | 9 (25) | 20 (24.6) | 0.972 |
Brainstem/cerebellum | 12 (33.3) | 13 (16) | 0.035* |
Lacunes | 8 (22.2) | 5 (6) | 0.022* |
Cerebral hemorrhage | 4 (9.8) | 18 (18.4) | 0.205 |
Basal ganglia | 2 (50) | 5 (28) | 0.565 |
Lobes | 1 (25) | 12 (66) | 0.264 |
Brainstem/cerebellum | 1 (25) | 1 (5) | 0.338 |
Medication | |||
rtPA | 4 (9.7) | 11 (11.2) | 0.799 |
Intervention | 3 (7) | 5 (5.1) | 0.693 |
In-hospital infections | |||
Lung infection | 13 (31.7) | 59 (60.2) | 0.002* |
Urinary tract infection | 0 (0) | 14 (14.3) | 0.011* |