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Table 1 Baseline characteristics

From: Pre-diabetes is a predictor of short-term poor outcomes after acute ischemic stroke using IV thrombolysis

 

NGM (=254)

Pre-DM (=197)

DM (=210)

p

Age

66.9 ± (13.7)

68.7 ± 12.6

70.7 ± 10.0

0.27

Female (%)

99 (38.9)

82 (41.6)

82 (39.1)

 

Hypertension (%)

135 (53.2)

110(55.8)

152 (72.4)

< 0.01

Smoking (%)

40 (15.8)

31 (15.7)

42 (20.0)

0.25

Hyperlipidemia (%)

42 (16.5)

39 (19.8)

86 (41.0)

< 0.01

Prior CAD (%)

29 (11.4)

31 (15.7)

39 (18.6)

0.09

Atrial fibrillation (%)

95 (37.4)

88 (44.7)

78 (37.1)

0.2

Prior stroke (%)

24 (9.5)

22 (11.2)

34 (16.2)

0.08

TOAST classification

   

0.48

 Large artery atherosclerosis (%)

54 (21.3)

45 (22.8)

59 (28)

 

 Cardioembolism (%)

95 (37.4)

85 (43.2)

74 (35.2)

 

 Small vessel occlusion (%)

36 (14.2)

20 (10.2)

20 (9.5)

 

 Other (%)

5 (2.0)

3 (1.5)

3 (1.4)

 

 Undetermined (%)

64 (25.2)

44 (22.3)

54 (25.7)

 

NIHSS (median)

9

10

9

 

NIHSS ≥ 10 (%)

129 (50.8)

117 (59.4)

114 (54.3)

0.91

Initial glucose

125.4 ± 25.7

133.9 ± 42.1

177.7 ± 70.6

< 0.01

Initial glucose ≥ 140 (%)

60 (23.6)

56 ± 28.4

132 ± 62.9

< 0.01

OTN (min, mean ± SD)

153.9 ± 119.9

155.5 ± 122.7

178.4 ± 170.1

0.82

Endovascular Tx (%)

84 (33.1)

64 (32.5)

69 (32.9)

0.99

END (%)

24 (9.5)

33 (16.8)

38 (18.1)

0.02

In hospital death (%)

5 (2.0)

14 (7.1)

17 (8.1)

< 0.01

poor outcome-90 days (%)

97 (38.2)

87 (44.2)

119 (56.7)

< 0.01

poor outcome − 1 year (%)

91 (35.8)

87 (44.2)

119 (56.7)

< 0.01

  1. NGM Normal glucose metabolism, DM Diabetes mellitus, CAD Coronary artery diseases, TOAST Trial of Org 10172 in Acute Stroke Treatment, OTN Onset to needle, END Early neurological deterioration