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Fig. 1 | BMC Neurology

Fig. 1

From: Single-shot bevacizumab for cerebral radiation injury

Fig. 1

MRI scans of a 34 year old patient with IDH-mutated astrocytoma. a MRI revealed a small recurrent tumor adjacent to the dorsal resection cavity with small surrounding edema. b The patient was treated with re-radiation therapy with 35 Gy and concomitant temozolomide. First MRI after the treatment showed an increase of contrast enhancement and edema which was diagnosed as radiation necrosis. c Therapy with 8 mg of dexamethasone did neither improve the MRI nor the clinical symptoms and bevacizumab 7.5 mg/kg was administered as a single-shot. d First scan one month later displayed a marked reduction in contrast enhancement and of the edema. Treatment with dexamethasone could be stopped. The follow up 3 months later was stable (not shown)

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