Table 1 Patient characteristics
Number of Patients | 11 |
Age at treatment with BEV [years] | |
Median (range) | 47 (22 – 73) |
Histology | |
Glioma | 91% (10) |
Brain metastasis (breast cancer) | 9% (1) |
Radiation for | |
Recurrent tumor | 82% (9) |
Primary therapy | 18% (2) |
Last radiation therapy prior to BEV [Gy] | |
5x4 | 18% (2) |
10x3 | 9% (1) |
10x3,5 | 36% (4) |
12x3 | 9% (1) |
15x2,67 | 9% (1) |
30x1,8 | 9% (1) |
30x2 | 9% (1) |
Time from radiation to diagnosis of radiation injury [months] | |
Median (range) | 2 (1-7) |
Maximum Dose of dexamethasone [mg] | |
Before therapy, Median (range) After therapy, Median (range) | 8 (0 – 40) 0 (0 - 4) |
Karnofsky-Score [%] | |
Before therapy, Median (range) | 50 (40 – 80) |
After therapy, Median (range) | 60 (40 – 80) |
Dose of BEV single-shot | |
7,5mg/kg | 73% (8) |
10mg/kg | 27% (3) |
Reported benefit by patient | |
Yes | 64% (7) |
No | 36% (4) |