Clinically accessible neuroimaging predictors of post-stroke neurocognitive disorder: a prospective observational study

Table 3 Results from logistic regression analyses with any or major neurocognitive disorder as outcome variable

Imaging marker		n	Any NCD OR [95%CI]	p-value	Major NCD OR [95%CI]	p-value
Stroke lesion volume (ml)	Unadjusted	231	1.01 [0.99 to 1.03]	0.176	1.04 [1.02 to 1.06]	0.001
Stroke lesion volume (ml)	Adjusted^a	231	1.01 [0.99 to 1.03]	0.275	1.04 [1.01 to 1.06]	0.001
WMH pathology	Unadjusted	231	2.73 [1.56 to 4.77]	0.001	3.09 [1.71 to 5.58]	0.001
WMH pathology	Adjusted^a	231	2.37 [1.33 to 4.23]	0.003	2.54 [1.33 to 4.84]	0.005
MTA pathology	Unadjusted	231	1.95 [1.12 to 3.41]	0.019	1.43 [0.79 to 2.59]	0.231
MTA pathology	Adjusted^a	231	2.13 [1.18 to 3.87]	0.013	1.87 [0.95 to 3.68]	0.069
Left hemispheric stroke	Unadjusted	226	1.80 [1.05 to 3.09]	0.032	1.12 [0.63 to 2.01]	0.693
Left hemispheric stroke	Adjusted^a	226	1.74 [1 to 3.04]	0.051	1.01 [0.53 to 1.93]	0.966
Strategic infarct	Unadjusted	231	1.05 [0.44 to 2.51]	0.91	1.13 [0.44 to 2.89]	0.796
Strategic infarct	Adjusted^a	231	1 [0.4 to 2.48]	1	1.17 [0.41 to 3.3]	0.770

The Odds Ratio (OR) of any NCD or major NCD in the presence of a defined imaging marker is shown in the table above. ORs are reported unadjusted and ^aadjusted for age, sex, and education

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