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Fig. 2 | BMC Neurology

Fig. 2

From: Exacerbation of myopathy triggered by antiobesity drugs in a patient with multiple acyl-CoA dehydrogenase deficiency

Fig. 2

Muscle pathology. The haematoxylin and eosin slide indicated mildly varied muscle fibre size and scattered small vacuoles (a). The ATPase stain (pH 4.6) demonstrated that the vacuoles were mainly in type 1 fibres (b, dark colour fibres). The modified Gomori trichrome stain showed no ragged red fibres (c). The oil red O stain revealed increased lipid droplets in size and number in scattered fibres (d, tiny red droplets). Transmission electron microscopy indicated increased lipid droplet and mitochondria counts (e), with abnormal cristae and some dense inclusion in mitochondria (e inset). (Scale bar, 100 μm in B1–B4 and 500 nm in B5)

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