Within 6 h | Beyond 6 h | p | |
---|---|---|---|
(n = 238) | (n = 67) | ||
Age, mean ± SD, y | 72.3 ± 1.6 | 66.9 ± 12.4 | 0.001 |
Male, n (%) | 135 (56.7) | 39 (58.2) | 0.828 |
Hypertension, n (%) | 171 (71.8) | 46 (68.7) | 0.610 |
Diabetes mellitus, n (%) | 53 (22.3) | 16 (23.9) | 0.781 |
Atrial fibrillation, n (%) | 131 (55.0) | 21 (31.3) | 0.001 |
Previous stroke/TIA, n (%) | 53 (22.3) | 14 (20.9) | 0.810 |
Smoking, n (%) | 77 (32.6) | 26 (38.8) | 0.324 |
Baseline NIHSS, median (IQR) | 16 (12–20) | 13 (9–17) | 0.002 |
Baseline ASPECT score, median (IQR) | 8 (6–9) | 7 (6–9) | 0.497 |
TOAST classification, n (%) | 0.006 | ||
Large artery atherosclerosis | 81 (34.0) | 37 (55.2) | |
Cardioembolism | 134 (56.3) | 24 (35.8) | |
Others | 23 (9.7) | 6 (9.0) | |
Occlusion site, n (%), | 0.746 | ||
Internal carotid artery | 84 (35.3) | 25 (37.3) | |
Middle cerebral artery M1 | 133 (55.9) | 38 (56.7) | |
Middle cerebral artery M2 | 21 (8.8) | 4 (6.0) | |
FBG, mmol/L, (n = 299) | 6.55 (5.33–8.17) | 6.53 (5.55–8.31) | 0.516 |
TC, mmol/L, (n = 297) | 4.08 (3.37–4.93) | 4.35 (3.51–5.12) | 0.123 |
TG, mmol/L, (n = 297) | 1.01 (0.74–1.47) | 1.20 (0.85–1.68) | 0.028 |
LDL, mmol/L, (n = 297) | 2.37 (1.86–3.01) | 2.75 (1.92–3.33) | 0.039 |
Intravenous thrombolysis, n (%) | 143 (60.1) | 11 (16.4) | < 0.001 |
Onset-to-groin puncture time, median (IQR), min | 215.5 (160.0–273.3) | 465.0 (395.0–670.0) | < 0.001 |
sICH | 16 (6.7) | 5 (7.5) | 0.833 |
In-hospital mortality | 18 (7.6) | 6 (9.0) | 0.709 |
Successful recanalization | 202 (84.9) | 55 (82.1) | 0.58 |
Favorable functional outcome at 90 days, (n = 294) | 85 (37.0) | 22 (34.4) | 0.704 |