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Table 1 Baseline characteristics of EVT patients treated within and beyond 6 h of onset

From: Endovascular treatment of acute ischemic stroke due to anterior circulation large vessel occlusion beyond 6 hours: a real-world study in China

 

Within 6 h

Beyond 6 h

p

(n = 238)

(n = 67)

Age, mean ± SD, y

72.3 ± 1.6

66.9 ± 12.4

0.001

Male, n (%)

135 (56.7)

39 (58.2)

0.828

Hypertension, n (%)

171 (71.8)

46 (68.7)

0.610

Diabetes mellitus, n (%)

53 (22.3)

16 (23.9)

0.781

Atrial fibrillation, n (%)

131 (55.0)

21 (31.3)

0.001

Previous stroke/TIA, n (%)

53 (22.3)

14 (20.9)

0.810

Smoking, n (%)

77 (32.6)

26 (38.8)

0.324

Baseline NIHSS, median (IQR)

16 (12–20)

13 (9–17)

0.002

Baseline ASPECT score, median (IQR)

8 (6–9)

7 (6–9)

0.497

TOAST classification, n (%)

  

0.006

 Large artery atherosclerosis

81 (34.0)

37 (55.2)

 

 Cardioembolism

134 (56.3)

24 (35.8)

 

 Others

23 (9.7)

6 (9.0)

 

Occlusion site, n (%),

  

0.746

 Internal carotid artery

84 (35.3)

25 (37.3)

 

 Middle cerebral artery M1

133 (55.9)

38 (56.7)

 

 Middle cerebral artery M2

21 (8.8)

4 (6.0)

 

FBG, mmol/L, (n = 299)

6.55 (5.33–8.17)

6.53 (5.55–8.31)

0.516

TC, mmol/L, (n = 297)

4.08 (3.37–4.93)

4.35 (3.51–5.12)

0.123

TG, mmol/L, (n = 297)

1.01 (0.74–1.47)

1.20 (0.85–1.68)

0.028

LDL, mmol/L, (n = 297)

2.37 (1.86–3.01)

2.75 (1.92–3.33)

0.039

Intravenous thrombolysis, n (%)

143 (60.1)

11 (16.4)

< 0.001

Onset-to-groin puncture time, median (IQR), min

215.5 (160.0–273.3)

465.0 (395.0–670.0)

< 0.001

sICH

16 (6.7)

5 (7.5)

0.833

In-hospital mortality

18 (7.6)

6 (9.0)

0.709

Successful recanalization

202 (84.9)

55 (82.1)

0.58

Favorable functional outcome at 90 days, (n = 294)

85 (37.0)

22 (34.4)

0.704

  1. Abbreviations: SD Standard deviation, TIA Transient ischemic attack, NIHSS National Institutes of Health Stroke Scale, IQR Interquartile range, ASPECT score Alberta Stroke Program Early CT Score, TOAST Trial of Org 10,172 in Acute Stroke Treatment, FBG Fasting blood glucose, TC Total cholesterol, TG Triglyceride, LDL Low-density lipoprotein, sICH Symptomatic intracranial hemorrhage