Table 1 Demographic and characteristics of young adults with MCA territory infarction
From: Prevalence and outcome of young stroke patients with middle cerebral artery stenosis
ALL (n = 249) | No-stenosis group (n = 139) | Stenosis group (n = 110) | P | Uni-MCA stenosis subgroup (n = 55) | Multiple stenosis subgroup (n = 55) | P | |
|---|---|---|---|---|---|---|---|
Age (yeras) | 48.0 + 6.0 | 47.8 + 5.7 | 48.3 + 6.4 | 0.151 | 47.5 + 7.7 | 49.1 + 4.7 | 0.723 |
Sex (male, %) | 170 (68.3%) | 96 (69.1%) | 74 (67.3%) | 0.763 | 38 (69.1%) | 36 (65.5%) | 0.684 |
Traditional risk factors | |||||||
Hypertension | 146 (58.6%) | 86 (61.9%) | 60 (54.5%) | 0.244 | 25 (45.5%) | 35 (63.6%) | 0.056 |
Diabetes mellitus | 73 (29.3%) | 34 (24.5%) | 39 (35.5%) | 0.058 | 17 (30.9%) | 22 (40.0%) | 0.319 |
CAD | 22 (8.8%) | 14 (10.1%) | 8 (7.3%) | 0.440 | 3 (5.5%) | 5 (9.1%) | 0.714 |
AF | 3 (1.2%) | 1 (0.7%) | 2 (1.8%) | 0.838 | 1 (1.8%) | 1 (1.8%) | 1.000 |
Hyperlipidemia | 137 (55.0%) | 83 (59.7%) | 54 (49.1%) | 0.094 | 27 (49.1%) | 27 (49.1%) | 1.000 |
Hyperhomocysteinemia | 90 (36.1%) | 53 (38.1%) | 37 (33.6%) | 0.464 | 19 (34.5%) | 18 (32.7%) | 0.840 |
Alcohol consumption | 84 (33.7%) | 47 (33.8%) | 37 (33.6%) | 0.927 | 14 (25.5%) | 23 (41.8%) | 0.069 |
Smoking | 102 (41%) | 55 (39.6%) | 47 (42.7%) | 0.615 | 25 (45.5%) | 22 (40.0%) | 0.563 |
TIA/stroke | 54 (21.7%) | 26 (18.7%) | 28 (25.5%) | 0.199 | 6 (10.9%) | 22 (40.0%) | 0.000 |
Family history of stroke | 48 (19.3%) | 25 (18.0%) | 23 (20.9%) | 0.561 | 12 (21.8%) | 11 (20.0%) | 0.815 |
Score of traditional risk factors | |||||||
≥ 2 | 208 (83.5%) | 115 (82.7%) | 93 (84.5%) | 0.702 | 43 (78.2%) | 50 (90.9%) | 0.065 |
≥ 3 | 152 (61.0%) | 87 (62.6%) | 65 (59.1%) | 0.574 | 28 (50.9%) | 47 (85.5%) | 0.000 |
Rare risk factors | |||||||
Other cardiac disease | 1 (0.4%) | 0 | 1 (0.4%) | – | 1 (0.4%) | 0 | – |
PAD | 2 (0.8%) | 0 | 2 (0.8%) | – | 1 (0.4%) | 1 (0.4%) | – |
Sleep apnea | 1 (0.4%) | 1 (0.4%) | 0 | – | 0 | 0 | – |
Migraine | 1 (0.4%) | 0 | 1 (0.4%) | – | 0 | 1 (0.4%) | – |
Autoimmune disease | 9 (3.6%) | 6 (4.3%) | 3 (2.7%) | – | 0 | 3 (5.5) | – |
Wake-up stroke | 16 (6.4%) | 7 (5.0%) | 9 (8.2%) | 0.315 | 4 (7.3%) | 5 (9.1%) | 1.000 |
NIHSS at admission | 4 (1, 8) | 3 (1, 6) | 6 (2, 11) | 0.000 | 6 (2, 12) | 5 (2, 11) | 0.827 |
Infarct size | |||||||
small infarct | 111 (44.6%) | 89 (64.0%) | 22 (20.0%) | 0.000 | 8 (14.5%) | 14 (25.5%) | 0.221 |
medium infarct | 82 (32.9%) | 44 (31.7%) | 38 (34.5%) | 18 (32.7%) | 20 (36.4%) | ||
large territorial infarct | 56 (22.5%) | 6 (4.3%) | 50 (45.5%) | 29 (52.7%) | 21 (38.2%) | ||
Silent brain infarcts | |||||||
0 | 133 (53.4%) | 71 (51.5%) | 62 (56.4%) | 0.385 | 43 (78.2%) | 19 (34.5%) | 0.000 |
1 | 30 (12.1%) | 15 (10.8%) | 15 (13.6%) | 5 (9.1%) | 10 (18.2%) | ||
≥ 2 | 86 (34.5%) | 53 (38.1%) | 33 (30.0%) | 7 (12.7%) | 26 (47.3%) | ||
White matter lesions | |||||||
0–2 | 168 (67.5%) | 92 (66.2%) | 76 (69.1%) | 0.626 | 42 (76.4%) | 34 (60.7%) | 0.182 |
3–4 | 63 (25.3%) | 35 (25.2%) | 28 (25.5%) | 11 (20.0%) | 17 (30.4%) | ||
5–6 | 18 (7.2%) | 12 (8.6%) | 6 (5.5%) | 2 (3.6%) | 5 (8.9%) | ||
Complications | 24 (9.6%) | 7 (5.0%) | 17 (15.5%) | 0.006 | 8 (14.5%) | 9 (16.4%) | 0.792 |
NIHSS at discharge | 2 (0, 5) | 2 (0, 4) | 4 (1, 8) | 0.000 | 4 (0, 8) | 4 (1, 7) | 0.904 |
mRS at discharge | |||||||
0–2 | 185 (74.3%) | 117 (84.2%) | 68 (61.8%) | 0.000 | 34 (61.8%) | 34 (61.8%) | 1.000 |
3–6 | 64 (25.7%) | 22 (15.8%) | 42 (38.2%) | 21 (38.2%) | 21 (38.2%) | ||