Skip to main content

Table 5 Relationship between frailty group and EQ-5D-5L dimensions

From: Association between in-hospital frailty and health-related quality of life after stroke: the Nor-COAST study

 

ROBUST

PREFRAIL

FRAIL

    

Difference from Robust

  

Difference from Robust

N

Mean (95% CI)

N

Mean (95% CI)

Estimate (95% CI)

p value

N

Mean (95% CI)

Estimate (95% CI)

p value

3 months

 Mobility

189

1.34 (1.22 to 1.47)

334

1.67 (1.58 to 1.76)

0.34 (0.19 to 0.50)

< 0.001

62

2.33 (2.11 to 2.55)

0.99 (0.74 to 1.25)

< 0.001

 Self-care

189

1.12 (1.02 to 1.21)

333

1.25 (1.18 to 1.31)

0.14 (0.03 to 0.25)

0.014

62

1.66 (1.51 to 1.82)

0.55 (0.37 to 0.74)

< 0.001

 Usual Activities

189

1.46 (1.33 to 1.59)

334

1.80 (1.70 to 1.88)

0.36 (0.19 to 0.52)

< 0.001

62

2.53 (2.31 to 2.76)

1.09 (0.82 to 1.35)

< 0.001

 Pain

187

1.61 (1.47 to 1.75)

333

1.91 (1.81 to 2.01)

0.29 (0.12 to 0.46)

0.001

62

2.01 (1.77 to 2.25)

0.39 (0.11 to 0.68)

0.007

 Anxiety

187

1.49 (1.37 to 1.60)

334

1.60 (1.52 to 1.69)

0.12 (−0.03 to 0.26)

0.118

61

1.74 (1.54 to 1.94)

0.25 (0.01 to 0.48)

0.038

18 months

 Mobility

175

1.36 (1.23 to 1.49)

282

1.78 (1.69 to 1.87)

0.43 (0.27 to 0.59)

< 0.001

41

2.81 (2.56 to 3.06)

1.45 (1.17 to 1.73)

< 0.001

 Self-care

175

1.13 (1.04 to 1.23)

283

1.32 (1.25 to 1.39)

0.20 (0.08 to 0.31)

0.001

41

1.94 (1.76 to 2.12)

0.81 (0.60 to 1.02)

< 0.001

 Usual Activities

175

1.42 (1.28 to 1.55)

283

1.73 (1.63 to 1.83)

0.34 (0.17 to 0.51)

< 0.001

41

2.64 (2.38 to 2.91)

1.24 (0.93 to 1.54)

< 0.001

 Pain

173

1.64 (1.50 to 1.79)

281

2.01 (1.91 to 2.12)

0.39 (0.21 to 0.57)

< 0.001

41

2.27 (1.99 to 2.55)

0.63 (0.31 to 0.95)

< 0.001

 Anxiety

175

1.45 (1.33 to 1.56)

282

1.56 (1.48 to 1.65)

0.14 (−0.01 to 0.29)

0.058

41

1.74 (1.51 to 1.97)

0.31 (0.04 to 0.57)

0.022

Change

 Mobility

194

0.02 (−0.09 to 0.14)

366

0.11 (0.02 to 0.20)

0.08 (−0.06 to 0.23)

0.251

65

0.48 (0.25 to 0.71)

0.46 (0.20 to 0.71)

< 0.001

 Self-care

194

0.02 (−0.07 to 0.10)

366

0.07 (0.01 to 0.14)

0.05 (−0.05 to 0.16)

0.351

65

0.28 (0.11 to 0.44)

0.26 (0.07 to 0.45)

0.007

 Usual Activities

194

−0.04 (−0.18 to 0.10)

366

−0.06 (−0.17 to 0.05)

−0.02 (−0.19 to 0.16)

0.851

65

0.11 (−0.17 to 0.39)

0.15 (−0.16 to 0.46)

0.335

 Pain

194

0.02 (−0.13 to 0.16)

366

0.11 (0.00 to 0.23)

0.10 (−0.09 to 0.28)

0.299

65

0.26 (−0.03 to 0.54)

0.24 (−0.08 to 0.56)

0.142

 Anxiety

194

−0.06 (−0.17 to 0.05)

366

−0.03 (−0.12 to 0.06)

0.03 (−0.12 to 0.17)

0.698

65

0.00 (−0.23 to 0.23)

0.06 (−0.19 to 0.31)

0.642

  1. Dependent variable: Mobility, Self-care, Daily Activities, Pain and Anxiety, respectively. Categorical covariate: frailty state. Random effect: participants
  2. Adjusted for age, sex, and NIHSS-score
  3. Range in each dimension: 1–5 points. Positive value in ‘change’ represents a worsening
  4. Relationship between frailty group and EQ-5D-5L dimensions at 3 and 18 months, respectively, and change in score between 3 and 18 months post stroke. Linear mixed effect regression with EQ-5D-5L dimension as dependent variable, frailty category and time between 3 and 18 months and their interaction as categorical covariates, and participant as random effect