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Table 5 Association of recurrent ipsilateral hemorrhage with clinical and vascular characteristics

From: Recurrent hemorrhage risk associated with medial target medullary artery anastomosis from the periventricular collateral vessel in adult patients with moyamoya disease

  Risk of Recurrent Hemorrhage
Univariate Analysis Multivariate Analysis
HR 95% CI p Value HR 95% CI p Value
Sex, female 1.01 0.33–3.14 0.985
Age 1.03 0.97–1.08 0.371
Smokers 1.28 0.17–9.71 0.812
Hypertension 0.79 0.27–2.28 0.662
Dyslipidemia 1.05 0.34–3.26 0.932
Diabetes mellitus 0.62 0.08–4.68 0.640
Advanced Suzuki stage 1.29 0.45–3.72 0.636
Involvement of PCA 1.43 0.50–4.13 0.507
Presence of posterior hemorrhage 1.27 0.46–3.49 0.646
Presence of ruptured collateral aneurysm 3.30 0.75–14.58 0.115
Target collateral vessel derived from ChA 1.51 0.49–4.68 0.477
Target anastomotic territory
 Nonmedullary artery anastomosis 0.14 0.02–1.04 0.054 0.11 0.01–1.03 0.053
 Lateral medullary artery anastomosis 1.09 0.41–2.94 0.858 0.56 0.15–2.13 0.397
 Medial medullary artery anastomosis 2.94 1.07–8.08 0.037 6.65 1.32–33.60 0.022
 Multiple medullary artery anastomosis 1.47 0.19–11.12 0.712 2.17 0.22–21.66 0.509
  1. PCA posterior cerebral artery, ChA choroidal artery
  2. Multivariate analysis was adjusted for confounding factors including initial age, sex, presence of posterior hemorrhage, target collateral vessel derived from the choroidal artery, advanced Suzuki stage, involvement of the posterior cerebral artery, and presence of ruptured collateral aneurysm
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