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Table 1 Participant summary characteristics

From: Retinal microvascular parameters are not significantly associated with mild cognitive impairment in the Northern Ireland Cohort for the Longitudinal Study of Ageing

Patient characteristics All (n = 1431) No MCI (n = 1275) MCI (n = 156) P-Value
Mean age (years, SD) 62.4 ± 8.5 62.1 ± 8.4 64.4 ± 8.8 < 0.01
Female, n (%) 750 (52.4) 680 (53.3) 70 (44.9) 0.05
Smoking status, yes n (%) 115 (8.0) 101 (7.9) 14 (9.0) 0.65
Alcohol consumption, non-drinker, n (%) 299 (20.9) 261 (20.5) 38 (24.4) 0.63
Education, secondary level and above, n (%) 1251 (87.4) 1133 (88.9) 118 (75.6) < 0.01
Physical activity level, highly active, n (%) 438 (30.6) 405 (31.8) 33 (21.2) 0.04
Diabetes, yes n (%) 308 (21.5) 275 (21.6) 33,921.2) 0.91
Mean BMI (kg/m2, SD) 28.2 ± 4.6 28.1 ± 4.6 28.9 ± 4.5 0.03
Mean arterial blood pressure (mmHg, SD) 98.1 ± 12.6 98.2 ± 12.6 97.1 ± 12.5 0.30
Cardiovascular disease, yes n (%) 90 (6.3) 72 (5.6) 18 (11.5) < 0.01
Hypertension, yes n (%) 432 (30.2) 372 (29.2) 60 (38.5) 0.02
Mean triglyceride (mmol/L, SD) 1.6 ± 0.9 1.6 ± 0.9 1.8 ± 1.2 0.01
Mean HDL cholesterol (mmol/L, SD) 1.6 ± 0.5 1.7 ± 0.5 1.6 ± 0.4 0.02
Mean MOCA test score (SD) 26.0 ± 2.8 26.3 ± 2.7 23.5 ± 2.6 < 0.01
  1. Values are n (%) for categorical variables and mean ± SD for continuous variables. P values were calculated by independent samples t and chi squared tests. Abbreviations: MCI mild cognitive impairment, BMI body mass index, HDL high-density lipoprotein, MoCA Montreal Cognitive Assessment, SD standard deviation. P < 0.05 was considered statistically significant