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Table 1 Participant summary characteristics

From: Retinal microvascular parameters are not significantly associated with mild cognitive impairment in the Northern Ireland Cohort for the Longitudinal Study of Ageing

Patient characteristics

All (n = 1431)

No MCI (n = 1275)

MCI (n = 156)

P-Value

Mean age (years, SD)

62.4 ± 8.5

62.1 ± 8.4

64.4 ± 8.8

< 0.01

Female, n (%)

750 (52.4)

680 (53.3)

70 (44.9)

0.05

Smoking status, yes n (%)

115 (8.0)

101 (7.9)

14 (9.0)

0.65

Alcohol consumption, non-drinker, n (%)

299 (20.9)

261 (20.5)

38 (24.4)

0.63

Education, secondary level and above, n (%)

1251 (87.4)

1133 (88.9)

118 (75.6)

< 0.01

Physical activity level, highly active, n (%)

438 (30.6)

405 (31.8)

33 (21.2)

0.04

Diabetes, yes n (%)

308 (21.5)

275 (21.6)

33,921.2)

0.91

Mean BMI (kg/m2, SD)

28.2 ± 4.6

28.1 ± 4.6

28.9 ± 4.5

0.03

Mean arterial blood pressure (mmHg, SD)

98.1 ± 12.6

98.2 ± 12.6

97.1 ± 12.5

0.30

Cardiovascular disease, yes n (%)

90 (6.3)

72 (5.6)

18 (11.5)

< 0.01

Hypertension, yes n (%)

432 (30.2)

372 (29.2)

60 (38.5)

0.02

Mean triglyceride (mmol/L, SD)

1.6 ± 0.9

1.6 ± 0.9

1.8 ± 1.2

0.01

Mean HDL cholesterol (mmol/L, SD)

1.6 ± 0.5

1.7 ± 0.5

1.6 ± 0.4

0.02

Mean MOCA test score (SD)

26.0 ± 2.8

26.3 ± 2.7

23.5 ± 2.6

< 0.01

  1. Values are n (%) for categorical variables and mean ± SD for continuous variables. P values were calculated by independent samples t and chi squared tests. Abbreviations: MCI mild cognitive impairment, BMI body mass index, HDL high-density lipoprotein, MoCA Montreal Cognitive Assessment, SD standard deviation. P < 0.05 was considered statistically significant