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Table 3 Logistic regression analysis of retinal microvascular parameters and Mild Cognitive Impairment status

From: Retinal microvascular parameters are not significantly associated with mild cognitive impairment in the Northern Ireland Cohort for the Longitudinal Study of Ageing

Retinal parameter

Minimally Adjusted

Fully Adjusted

OR

95% CI

P-Value

OR

95% CI

P-Value

aCRAE (PX)

1.04

0.88, 1.23

0.66

1.04

0.88, 1.24

0.63

aCRVE (PX)

0.95

0.80, 1.12

0.53

0.96

0.81, 1.14

0.67

aAVR

1.08

0.92, 1.28

0.35

1.07

0.90, 1.28

0.42

aFractal dimension arteriolar

0.98

0.83, 1.15

0.80

0.93

0.79, 1.10

0.42

aFractal dimension venular

1.00

0.85, 1.18

0.98

0.97

0.82, 1.15

0.69

abTortuosity arteriolar

1.12

0.95, 1.32

0.19

1.09

0.92, 1.29

0.30

abTortuosity venular

0.97

0.82, 1.15

0.76

0.97

0.82, 1.16

0.75

  1. Abbreviations: CRAE central retinal arteriolar equivalent, CRVE central retinal venular equivalent, AVR retinal arteriole/venular ratio, CI confidence interval, OR odds ratio, PX pixels. aRMPs were transformed into standardised Z-scores before inclusion in regression models. bTortuosity values were skewed and therefore log-transformed before inclusion in regression models. Minimally adjusted model: age and sex. Fully adjusted model: age, sex, alcohol consumption, smoking status, educational attainment, physical activity, history of cardiovascular disease, hypertension, triglycerides, diabetes, medication, mean arterial blood pressure, body mass index and high density lipoprotein. P < 0.05 was considered statistically significant