Identification of upregulated NF-κB inhibitor alpha and IRAK3 targeting lncRNA following intracranial aneurysm rupture-induced subarachnoid hemorrhage

Table 1 KEGG pathways associated with LINC00265 and LINC00937 and the target genes

Name	SIZE	ES	NES	NOM p-val	Gene
LINC00265
Cytokine-cytokine receptor interaction	3	0.7413	1.5656	0.0042	IL4R
Neurotrophin signaling pathway	2	0.6761	1.2246	0.0226	IRAK3,MAPK14
Apoptosis	2	0.6731	1.2001	0.0269	IRAK3, CFLAR
Neuroactive ligand receptor interaction	2	0.5909	1.1584	0.0309	C3AR1, FPR2
LINC00937
Apoptosis	3	−0.7738	−1.6314	0.0036	IRAK3, CFLAR, NFKBIA
Toll like receptor signaling pathway	6	−0.4242	−1.2428	0.0178	NFKBIA,MAPK14,TLR8,TLR5,TLR4,TLR2
Neurotrophin signaling pathway	3	−0.5119	−1.0841	0.0353	IRAK3,NFKBIA,MAPK14
Cytokine-cytokine receptor interaction	4	0.6016	1.4480	0.0080	IL1R2,IL18RAP,IL18R1
MAPK signaling pathway	3	0.5000	0.9982	0.0489	IL1R2,MKNK1,MAPK14

ISSN: 1471-2377