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Table 2 Clinical characteristics of 8 cases with surgically resected SEGA associated with TSC

From: Experience using mTOR inhibitors for subependymal giant cell astrocytoma in tuberous sclerosis complex at a single facility

Patient no.

Sex

Age at operation

Date of operation

Approaches to the SEGA

Symptoms of SEGA (reason for surgery)

1

M

6

pre-mTORi era

surgical removal

enlarged lateral ventricle (prophylactic)

2

M

10

pre-mTORi era

surgical removal (+ frontal lobe focus resection)

enlarged lateral ventricle (prophylactic)

3

F

19

pre-mTORi era

surgical removal (emergency)

acute hydrocephalus (cure of iICP)

4

F

6

pre-mTORi era

VP shunt, then surgical removal

enlarged lateral ventricle (prophylactic)

5

M

12

pre-mTORi era

surgical removal

none (prophylactic)

6

M

7

pre-mTORi era

surgical removal, then VP shunt

enlarged lateral ventricle (prophylactic)

7

M

9

post-mTORi era

surgical removal

none (prophylactic)

8

F

1

post-mTORi era

surgical removal (+ total corpus callosotomy)

none (prophylactic)

  1. F Female, M Male, SEGA Subependymal giant cell astrocytoma, VP shunt Ventriculoperitoneal shunt, iICP Increased intracranial pressure