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Table 1 The baseline characteristics between good outcome and death/severe disability groups

From: Plasma D-dimer level is associated with clinical outcomes in patients with atrial fibrillation related acute ischemic stroke after pneumonia

 

Good outcome group (187)

Death/severe disability group (228)

OR(95%CI)

P*

Age, y (Mean SD)

66.32 ± 9.97

68.68 ± 9.63

 

0.005

NIHSS score, median (IQR)

7(5–11)

13(10–16)

 

<0.001

D-dimer, median (IQR)

1.30(0.80–2.00)

2.50(1.60–3.88)

 

<0.001

INR, median (IQR)

1.34(1.06–1.97)

1.37(1.10–1.93)

 

0.838

CHA2DS2-VASc, median (IQR)

4.00(4–5)

4.0(4–5)

 

0.360

Infarct volume, ml, median (IQR)

51(29–76)

81(50–127)

 

<0.001

CURB-65 score, median (IQR)

2(1–2)

2(1–3)

 

0.005

Females, n(%)

88(47.06)

123(53.95)

1.32 (0.89–1.94)

0.163

Male, n(%)

99(52.94)

105(46.05)

1.32 (0.89–1.94)

0.163

BMI ≥ 24 kg/m, n(%)

55(29.41)

68(29.82)

1.02(0.67–1.56)

0.927

Hypertension, n(%)

120(64.17)

145(63.60)

0.98(0.65–1.46)

0.904

Current Smoking, n(%)

51(27.27)

75(32.89)

1.31(0.86–2.00)

0.215

Current alcohol drinking,n(%)

66(35.29)

81(35.53)

1.01(0.67–1.51)

0.961

Diabetes, n(%)

58(31.01)

65(28.51)

0.89(0.58–1.35)

0.578

Hyperlipidemia, n(%)

121(64.71)

157(68.86)

1.21(0.80–1.82)

0.371

Family history of stroke, n(%)

46(24.60)

48(21.05)

0.82(0.52–1.30)

0.390

Thrombolytic therapy, n(%)

26(13.90)

25(10.96)

0.76(0.42–1.37)-

0.763

Thrombectomy, n(%)

10(5.35)

13(5.70)

1.07(0.46–2.50)

0.875

Thrombolytic therapy+ Thrombectomy, n(%)

4(2.14)

4(1.75)

0.82(0.20–3.31)

0.777

Medications use

 Antihypertensive, n(%)

96(51.34)

133(58.33)

1.38(0.90–1.96)

0.154

 Anticoagulant, n(%)

61(32.62)

21(9.21)

0.21(0.12–0.36)

0.000

 Antiplatelets, n(%)

54(28.88)

55(24.12)

0.78(0.51–1.21)

0.274

 Lipid-lowering medications, n(%)

109(58.29)

132(57.89)

0.98(0.67–1.46)

0.935

  1. Bold indicates P-values less than 0.05.
  2. *Comparison between good outcome and death/severe disability groups. The data are presented as median values (interquartile range [IQR]), numbers (%), or mean values (±standard deviation). Categorical variables are expressed as frequency (percent) for P values. Baseline characteristics were compared between the 2 subgroups by univariate analysis using Pearson χ2, distributions of continuous variables were determined by the Kolmogorov–Smirnov test, Mann–Whitney two sample test was applied in case of non-normal distributions