Fig. 1

Brain MRI showed a representative case of a patient with NMOSD. a. A T2-weighted hyperintensity lesion at the area postrema that extended to the first cervical vertebral body level on the MRI sagittal view. b. The brain MRI axial view showed a hyperintense lesion at the area postrema that was more severe on the left side of the medulla. c. A [Gd]-enhanced lesion from the medulla to the first cervical vertebral body level on the sagittal-view T1-weighted contrast image. d. A hyperintense lesion from the area postrema extended to the secondary vertebral body level on the sagittal-view FLAIR image was noted 2 years after the first attack