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Table 2 Comparison of peripheral blood lymphocyte subsets between the ALS-ci group and the ALS-nci group

From: Decreased blood CD4+ T lymphocyte helps predict cognitive impairment in patients with amyotrophic lateral sclerosis

Lymphocyte subsets

ALS-nci (49 patients)

ALS-ci (32 patients)

P value

Total T (#)

1247.00 [962.50–1375.00]

996.50 [785.50–1149.50]

0.005

CD4+ T (#)

767.63 ± 224.23

652.47 ± 190.75

0.019

CD8+ T (#)

360.00 [277.00–466.00]

262.00 [210.00–432.50]

0.019

B (#)

219.00 [144.00–297.50]

158.50 [136.25–213.00]

0.035

NK (#)

179.00 [132.00–284.50]

194.00 [115.50–376.75]

0.896

Total T (%)

73.36 [68.06–76.55]

68.97 [63.80–78.74]

0.284

CD4+ T (%)

45.75 ± 7.94

44.79 ± 8.06

0.598

CD8+ T (%)

22.75 ± 6.24

21.03 ± 7.92

0.309

B (%)

13.60 ± 4.76

12.89 ± 4.97

0.519

NK (%)

11.51 [9.32–18.54]

13.96 [8.91–20.74]

0.356

CD4+/CD8+ ratio

2.01 [1.59–2.73]

2.15 [1.69–3.47]

0.484

  1. Significant P values were shown in bold
  2. Abbreviations: ALS-nci ALS without cognitive impairment, ALS-ci ALS with cognitive impairment. (#) = cell count of each lymphocyte subset; (%) = lymphocyte subset count/ total lymphocyte count