Table 2 Genotype, allele frequency and phenotype of Vitamin D-Binding Protein Gene in MS and control groups
From: Reduction in circulating vitamin D binding protein in patients with multiple sclerosis
|  | MS (N = 296) | Control (N = 313) | p-value |
|---|---|---|---|
Genotype- rs4588 | |||
 CC (Thr/Thr) | 48.6% (144) | 50.2% (157) | 0.88 |
 AA (Lys/Lys) | 8.8% (26) | 9.3% (29) |  |
 AC (Lys/Thr) | 42.6% (126) | 40.6% (127) |  |
Genotype- rs7041 | |||
 TT (Asp/Asp) | 20.9% (62) | 25.6% (80) | 0.36 |
 GG (Glu/Glu) | 29.1% (86) | 25.9% (81) |  |
 TG (Asp/Glu) | 50.0% (148) | 48.6% (152) |  |
allele Freq. rs4588 | |||
 C | 0.6993 | 0.7044 | 0.84 |
 A | 0.3006 | 0.2955 |  |
allele Freq.rs7041 | |||
 T | 0.4594 | 0.4984 | 0.17 |
 G | 0.5405 | 0.5015 |  |
GC phenotype | |||
 Gc1f, Gc1f | 4.1% (12) | 5.8% (18) | 0.65 |
 Gc1s, Gc1s | 28.4% (84) | 24.6% (77) |  |
 Gc2, Gc2 | 8.1% (24) | 8.0% (25) |  |
 GC1f,GC1s | 17.9% (53) | 20.1% (63) |  |
 GC1f,GC2 | 10.1% (30) | 12.8% (40) |  |
 GC1s,GC2 | 30.7% (91) | 27.5% (86) |  |
 Rare | 0.7% (2) | 1.3% (4) |  |