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Table 2 Top 20 diagnoses for predicting PD immediately prior to PD diagnosis

From: Accelerating diagnosis of Parkinson’s disease through risk prediction

Description

OR

FDR Adjusted P Value

PD Prevalance

non-PD Prevalance

Abnormality of gait

8.31

2.80E-188

15.91%

2.05%

Abnormal involuntary movements

55.96

1.49E-168

19.67%

0.35%

Malaise and fatigue

3.53

2.33E-112

20.78%

6.27%

Essential tremor

38.04

1.96E-79

8.30%

0.23%

Depression

4.07

2.96E-76

10.96%

2.94%

Back pain

2.53

2.98E-62

16.11%

7.34%

Essential hypertension

1.57

3.41E-57

42.66%

31.15%

Dizziness and giddiness (Light-headedness and vertigo)

3.08

2.08E-54

12.11%

4.25%

Anxiety disorder

3.51

1.72E-51

8.51%

2.67%

Major depressive disorder

4.16

1.73E-47

4.74%

1.17%

Pain in joint

1.98

6.84E-46

21.10%

12.25%

Constipation

3.52

5.03E-42

7.73%

2.39%

Spondylosis without myelopathy

2.68

5.19E-40

11.21%

4.13%

Lack of coordination

10.97

1.63E-39

4.29%

0.37%

Pain in limb

2.26

6.99E-35

13.70%

6.76%

Extrapyramidal disease and abnormal movement disorders

51.01

8.70E-35

4.42%

0.09%

Abdominal pain

2.19

1.43E-33

12.52%

6.34%

Type 2 diabetes

1.78

4.41E-32

13.33%

8.94%

Urinary incontinence

3.46

9.38E-32

5.03%

1.69%